Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3274469 | 0.89 | GNRHR (1.00) | GNRHRHTR2A | |
| SCHEMBL4458782 | 0.84 | GNRHR (0.81) | GNRHRHTR2A | |
| SCHEMBL4459303 | 0.83 | GNRHR (0.75) | GNRHRHTR2A | |
| SCHEMBL4461442 | 0.83 | GNRHR (0.75) | GNRHRHTR2A | |
| SCHEMBL4459787 | 0.81 | GNRHR (0.80) | GNRHRHTR2A | |
| SCHEMBL4475211 | 0.77 | GNRHR (0.79) | GNRHRHTR2A | |
| SCHEMBL4468013 | 0.77 | GNRHR (1.00) | GNRHR | |
| SCHEMBL4459877 | 0.77 | GNRHR (0.63) | GNRHR | |
| SCHEMBL3276075 | 0.76 | GNRHR (0.77) | GNRHRHTR2A | |
| SCHEMBL4466526 | 0.76 | GNRHR (0.80) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582634-B2 | 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-09-01 | — | — | US | claimed |
| US-20060189616-A1 | 7-Substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2006-08-24 | — | — | US | claimed |
| US-7582634-B2 | 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-20060189616-A1 | 7-Substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189616-A1 | 7-Substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor | GNRHR, LHCGR, FSHR | GNRHR 1/4885HTR2A 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.