Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.60 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.60 |
| ▸ | ITGAL | P20701 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4472047 | 1.00 | ITGB2 (0.60) | ITGB2ICAM1ITGAL | |
| SCHEMBL5990881 | 0.93 | ITGB2 (0.59) | ITGB2ICAM1ITGAL | |
| SCHEMBL5990887 | 0.93 | ITGB2 (0.59) | ITGB2ICAM1ITGAL | |
| SCHEMBL4464784 | 0.89 | ITGB2 (0.60) | ITGB2ICAM1ITGAL | |
| SCHEMBL4474730 | 0.89 | ITGB2 (0.60) | ITGB2ICAM1ITGAL | |
| SCHEMBL4462932 | 0.88 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL4462940 | 0.88 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL14566293 | 0.86 | ITGB2 (0.68) | ITGB2ICAM1ITGAL | |
| SCHEMBL4461725 | 0.85 | ITGB2 (0.63) | ITGB2ICAM1ITGAL | |
| SCHEMBL5990711 | 0.85 | ITGB2 (0.63) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517897-B2 | Derivatives of 6,7-dihydro-5h -imidazo[1,2-a] imidazole-3-sulfonic acid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-14 | — | — | US | disclosed |
| US-7517897-B2 | Derivatives of 6,7-dihydro-5h -imidazo[1,2-a] imidazole-3-sulfonic acid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-14 | — | — | US | disclosed |
| WO-2007027233-A2 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-A]IMIDAZOLE-3-SULFONIC ACID | BOEHRINGER INGELHEIM INTERNATIONAL, GMBH (DE) | 2007-03-08 | — | — | WO | disclosed |
| US-20060264472-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a] IMIDAZOLE-3-SULFONIC ACID | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264472-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a] IMIDAZOLE-3-SULFONIC ACID | HPGDS, ICAM1, HCLS1 | ITGB2 442/4885ICAM1 2/4885ITGAL 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.