Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 1/20 | 0.68 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.64 |
| ▸ | MET | P08581 | 16/20 | 0.60 |
| ▸ | KDR | P35968 | 2/20 | 0.58 |
| ▸ | KIT | P10721 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4475152 | 0.99 | FGFR2 (0.67) | FGFR2PDGFRAMETKDRKIT | |
| SCHEMBL13936798 | 0.98 | FGFR2 (0.65) | FGFR2PDGFRAMETKDRKIT | |
| Hydrochloric Acid SCHEMBL4475260 | 0.97 | FGFR2 (0.64) | FGFR2PDGFRAMETKDRKIT | |
| SCHEMBL4471841 | 0.96 | PDGFRA (0.65) | FGFR2PDGFRAMETKDRKIT | |
| Hydrochloric Acid SCHEMBL4476484 | 0.95 | PDGFRA (0.64) | FGFR2PDGFRAMETKDRKIT | |
| SCHEMBL4472967 | 0.94 | PDGFRA (0.60) | FGFR2PDGFRAMETKDR | |
| Hydrochloric Acid SCHEMBL4483716 | 0.93 | PDGFRA (0.59) | FGFR2PDGFRAMETKDR | |
| SCHEMBL4472845 | 0.93 | PDGFRA (0.62) | FGFR2PDGFRAMETKDRKIT | |
| SCHEMBL4489534 | 0.93 | MET (0.68) | FGFR2METKDR | |
| SCHEMBL4461094 | 0.93 | MET (0.68) | FGFR2METKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7495104-B2 | Quinoline or quinazoline derivatives inhibiting auto-phosphorylation of fibroblast growth factor receptors | KIRIN BEER KABUSHIKI KAISHA (JP) | 2009-02-24 | — | — | US | claimed |
| US-7495104-B2 | Quinoline or quinazoline derivatives inhibiting auto-phosphorylation of fibroblast growth factor receptors | KIRIN BEER KABUSHIKI KAISHA (JP) | 2009-02-24 | — | — | US | disclosed |
| US-7495104-B2 | Quinoline or quinazoline derivatives inhibiting auto-phosphorylation of fibroblast growth factor receptors | KIRIN BEER KABUSHIKI KAISHA (JP) | 2009-02-24 | — | — | US | disclosed |