Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4472174 | 0.92 | MAPT (0.51) | MAPTCRHBPCRHR2L3MBTL1ALDH1A1 | |
| SCHEMBL4656215 | 0.86 | DRD2 (0.57) | MAPTCRHBPCRHR2L3MBTL1ALDH1A1 | |
| SCHEMBL4613807 | 0.85 | MAPT (0.52) | MAPTCRHBPCRHR2L3MBTL1ALDH1A1 | |
| SCHEMBL4612581 | 0.84 | MAPT (0.57) | MAPTCRHBPCRHR2L3MBTL1ALDH1A1 | |
| SCHEMBL4864396 | 0.84 | MAPT (0.54) | MAPTCRHBPCRHR2L3MBTL1ALDH1A1 | |
| SCHEMBL831256 | 0.83 | MAPT (0.58) | MAPTCRHBPCRHR2L3MBTL1ALDH1A1 | |
| SCHEMBL28536387 | 0.83 | MAPT (0.58) | MAPTCRHBPCRHR2L3MBTL1ALDH1A1 | |
| SCHEMBL93219 | 0.83 | MAPT (0.58) | MAPTCRHBPCRHR2L3MBTL1ALDH1A1 | |
| SCHEMBL4832130 | 0.83 | MAPT (0.58) | MAPTCRHBPCRHR2L3MBTL1ALDH1A1 | |
| SCHEMBL3032142 | 0.81 | MAPT (0.61) | MAPTCRHBPCRHR2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595181-B2 | From thermophilic microorganisms; active at high temperature | PROTEUS S.A. (FR) | 2009-09-29 | — | — | US | claimed |
| US-7595181-B2 | From thermophilic microorganisms; active at high temperature | PROTEUS S.A. (FR) | 2009-09-29 | — | — | US | disclosed |
| EP-1668124-A2 | THERMOSTABLE HYDROLASE | Goldschmidt GmbH (DE) | 2006-06-14 | — | — | EP | disclosed |
| US-20060008887-A1 | Production of carboxylic acid and carbonic acid derivatives using a thermostable esterase | GOLDSCHMIDT AG (DE) | 2006-01-12 | — | — | US | disclosed |
| US-20050112644-A1 | Thermostable hydrolase | EVONIK GOLDSCHMIDT GMBH (DE) | 2005-05-26 | — | — | US | disclosed |
| WO-2005040370-A2 | THERMOSTABLE HYDROLASE | GOLDSCHMIDT GMBH (DE) | 2005-05-06 | — | — | WO | disclosed |