SCHEMBL447247

SCHEMBL447247

[CH2]C1=NCCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL446069 0.82
SCHEMBL28428254 0.71 NISCH (0.60)
SCHEMBL9191340 0.67
SCHEMBL7086233 0.67
SCHEMBL646639 0.67
SCHEMBL2367035 0.67
SCHEMBL246346 0.67
SCHEMBL5425637 0.67
SCHEMBL20213848 0.67
SCHEMBL171997 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0300665-B1 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions ZENECA PHARMA SA (FR) 1995-12-20 EP claimed
EP-0304155-B1 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions ZENECA PHARMA SA (FR) 1995-11-15 EP claimed
EP-0225182-B1 CEPHALOSPORIN COMPOUNDS ICI PHARMA (FR) 1993-02-10 EP claimed
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP claimed
US-5013731-A Bactericides ICI PHARMA (FR) 1991-05-07 US claimed
US-5008258-A Antibiotics I.C.I.-PHARMA (FR) 1991-04-16 US claimed
EP-0164944-B1 CEPHALOSPORIN DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-07-11 EP claimed
US-4868173-A CONTAIN AMINE SALT GROUP ICI PHARMA (FR) 1989-09-19 US claimed
EP-0304155-A2 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions ZENECA Pharma S.A. (FR) 1989-02-22 EP claimed
EP-0300665-A2 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions ZENECA Pharma S.A. (FR) 1989-01-25 EP claimed
EP-0300664-A2 Cephalosporin compounds ZENECA Pharma S.A. (FR) 1989-01-25 EP claimed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US claimed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP claimed
EP-0225182-A2 Cephalosporin compounds ICI PHARMA (FR) 1987-06-10 EP claimed
EP-0182633-A2 Cephalosporin derivatives ICI PHARMA (FR) 1986-05-28 EP claimed
EP-0164944-A1 Cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-12-18 EP claimed
US-20140335517-A1 DETECTION AND TREATMENT OF SCHIZOPHRENIA RENASCIENCE CO LTD (JP) 2014-11-13 US disclosed
US-8809329-B2 Detection and treatment of schizophrenia TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE (JP) 2014-08-19 US disclosed
EP-0182633-A2 Cephalosporin derivatives ICI PHARMA (FR) 1986-05-28 EP disclosed
EP-0164944-A1 Cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-12-18 EP disclosed