Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | NSD2 | O96028 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11421896 | 0.84 | MAPT (0.69) | MAPTMAPK1NSD2KDM4EALDH1A1 | |
| SCHEMBL4480618 | 0.82 | MAPT (0.72) | MAPTMAPK1NSD2KDM4EHDAC4 | |
| SCHEMBL1782448 | 0.82 | HTR7 (0.50) | MAPTMAPK1NSD2KDM4EHDAC4 | |
| SCHEMBL4465042 | 0.81 | MAPT (0.89) | MAPTMAPK1NSD2KDM4EALDH1A1 | |
| SCHEMBL285567 | 0.78 | MAPT (0.89) | MAPTMAPK1NSD2KDM4EALDH1A1 | |
| Anthraquinone SCHEMBL11411972 | 0.78 | MAPT (0.89) | MAPTMAPK1NSD2KDM4EALDH1A1 | |
| SCHEMBL30475313 | 0.78 | MAPT (0.89) | MAPTMAPK1NSD2KDM4EALDH1A1 | |
| SCHEMBL6366580 | 0.78 | ADORA2A (0.58) | MAPTMAPK1NSD2KDM4EALDH1A1 | |
| SCHEMBL4469259 | 0.78 | MAPK1 (0.56) | MAPTMAPK1NSD2KDM4EALDH1A1 | |
| SCHEMBL11424452 | 0.78 | HDAC4 (0.52) | MAPTMAPK1NSD2HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7494721-B2 | Light-emitting device, condensed polycyclic compound used therein and method for producing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2009-02-24 | — | — | US | disclosed |
| US-20060051612-A1 | Light-emitting device, condensed polycyclic compound used therein and method for producing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2006-03-09 | — | — | US | disclosed |
| EP-1589089-A1 | LIGHT-EMITTING DEVICE, CONDENSED POLYCYCLIC COMPOUND USED THEREIN AND METHOD FOR PRODUCING SAME | Nippon Kayaku Kabushiki Kaisha (JP) | 2005-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060051612-A1 | Light-emitting device, condensed polycyclic compound used therein and method for producing same | CYBA, SCO2, NQO1 | MAPT 2457/4885MAPK1 2071/4885NSD2 941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.