SCHEMBL4476369

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4481629	0.87	CSNK2A1 (0.46)	MAPTTRPV1AURKACSNK2A2CSNK2B
	SCHEMBL4486500	0.85	TACR3 (0.51)	HTTKDM4EMAPTALDH1A1MEN1
	SCHEMBL13973637	0.77	NPC1 (0.58)	HTTKDM4EMAPTALDH1A1MEN1
	SCHEMBL13961569	0.72	NPC1 (0.46)	HTTKDM4EMAPTALDH1A1KDR
	SCHEMBL4503390	0.72	PIM1 (0.55)	MEN1KMT2ACSNK2A2CSNK2BCSNK2A1
	SCHEMBL4490345	0.72	FABP3 (0.51)	HTTKDM4EMAPTALDH1A1MEN1
	SCHEMBL13973657	0.72	MAPT (0.48)	HTTKDM4EMAPTALDH1A1KDR
	SCHEMBL27515136	0.71	MEN1 (0.62)	HTTKDM4EMAPTALDH1A1MEN1
	SCHEMBL13973635	0.70	NPC1 (0.59)	KDM4EMAPTALDH1A1MEN1KMT2A
	SCHEMBL13973636	0.69	MAPK10 (0.51)	HTTKDM4EMAPTALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.