SCHEMBL4476401

SCHEMBL4476401

CC(C)CN=NCC(C)C#N

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
TRPA1 O75762 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6522065 0.92 TSHR (0.43) TSHR
SCHEMBL121 0.92 TSHR (0.43) TSHR
SCHEMBL142610 0.92 TSHR (0.43) TSHR
Hydrochloric Acid SCHEMBL9508593 0.89 TSHR (0.42) TSHR
SCHEMBL10454453 0.89 TSHR (0.42) TSHR
Cyclohexane SCHEMBL9580757 0.84 TSHR (0.39) TSHR
Alcohol SCHEMBL11052439 0.82 TSHR (0.37) TSHR
SCHEMBL7745657 0.81 TSHR (0.33) TSHRTRPA1
SCHEMBL10578912 0.81 TSHR (0.43) TSHRTRPA1
SCHEMBL9860811 0.81 TSHR (0.46) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0220751-A2 Foamable and cross-linkable unsaturated polyester composition PENNWALT CORPORATION (US) 1987-05-06 EP claimed
EP-2111380-B1 REDUCED FOULING OF REVERSE OSMOSIS MEMBRANES PUROLITE COMPANY (US) 2015-10-28 EP disclosed
US-8883012-B2 Reduced fouling of reverse osmosis membranes PUROLITE CORPORATION (US) 2014-11-11 US disclosed
US-8496121-B2 High crush strength crosslinked ion exchange resins; suspension polymerization; filter cake cleaning fluid and/or gas streams THE PUROLITE COMPANY (US) 2013-07-30 US disclosed
EP-2111380-A1 REDUCED FOULING OF REVERSE OSMOSIS MEMBRANES The Purolite Company (US) 2009-10-28 EP disclosed
US-20080237133-A1 MACROPOROUS COPOLYMERS WITH LARGE PORES THE PUROLITE COMPANY (US) 2008-10-02 US disclosed
WO-2008118972-A1 MACROPOROUS COPOLYMERS WITH LARGE PORES THE PUROLITE COMPANY (US) 2008-10-02 WO disclosed
US-20080173583-A1 using a highly porous ion exchange resin ( polysodium styrenesulfonate, polyacylamide-N-propyltrimethylammonium chloride) for pretreatment of water being fed to a reverse osmosis; reduces deposits or chemical attack on the membrane surfaces and passageways THE PUROLITE COMPANY (US) 2008-07-24 US disclosed
WO-2008089279-A1 REDUCED FOULING OF REVERSE OSMOSIS MEMBRANES THE PUROLITE COMPANY (US) 2008-07-24 WO disclosed
EP-1048476-B1 Time-temperature medium and use NCR INT INC (US) 2005-10-12 EP disclosed
US-6524000-B1 A recording material comprising a base sheet suitable for feeding into a thermal printer, wherein said thermal printer is suitable for generating a thermal image on thermal paper, NCR CORPORATION 2003-02-25 US disclosed
US-6517239-B1 Time-temperature indicators activated with thermal transfer printing and methods for their production NCR CORPROATION 2003-02-11 US disclosed
US-6323249-B1 CROSSLINKING MACROPOROUS RESIN WITH HIGH STRENGTH FOR ETHYLENE MONOMER, POLYETHYLENE, FREE RADICAL INITIATORS AND POLYOXYETHYLENE PORE FORMING AGENT WITH TOLUENE PUROLITE INTERNATIONAL, LTD. (GB) 2001-11-27 US disclosed
US-6228299-B1 FORMING INORGANIC POWDERS, SLURRYING INORGANIC POWDER IN SOLVENT AND POLYMERIZATION OF MONOMER UT-BATTELLE, LLC 2001-05-08 US disclosed
EP-1048476-A1 Time-temperature indicators activated with thermal transfer printing and methods for their production NCR INTERNATIONAL INC. (US) 2000-11-02 EP disclosed
EP-1048477-A1 Time-temperature indicators activated with direct thermal printing and methods for their production NCR INTERNATIONAL INC. (US) 2000-11-02 EP disclosed
EP-0227048-A2 Peroxide concentrate and polymer carrier Albee, Paul J., Jr. (US) 1987-07-01 EP disclosed
EP-0135292-A1 A method of preparing a highly porous resin DUOLITE INTERNATIONAL, INC. (US) 1985-03-27 EP disclosed
US-4306039-A ACRYLIC ESTER COPOLYMERS AND VINYL AMIDE HOMO OR COPOLYMERS THE KENDALL COMPANY (US) 1981-12-15 US disclosed
US-3999946-A CONJUGATED ACETYLENE GROUP CONTAINING COMPOUND FOR USE ON PERISHABLE FOODS ALLIED CHEMICAL CORPORATION (US) 1976-12-28 US disclosed