Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6522065 | 1.00 | TSHR (0.43) | TSHR | |
| SCHEMBL121 | 1.00 | TSHR (0.43) | TSHR | |
| Hydrochloric Acid SCHEMBL9508593 | 0.97 | TSHR (0.42) | TSHR | |
| SCHEMBL10454453 | 0.97 | TSHR (0.42) | TSHR | |
| SCHEMBL4476401 | 0.92 | TSHR (0.39) | TSHR | |
| Cyclohexane SCHEMBL9580757 | 0.92 | TSHR (0.39) | TSHR | |
| Alcohol SCHEMBL11052439 | 0.89 | TSHR (0.37) | TSHR | |
| SCHEMBL9860811 | 0.88 | TSHR (0.46) | TSHR | |
| SCHEMBL7066390 | 0.86 | TSHR (0.44) | TSHR | |
| Formamide SCHEMBL15106454 | 0.85 | TSHR (0.34) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595265-B2 | Inhibitors of activin receptor-like kinase | BLUEPRINT MEDICINES CORPORATION (US) | 2026-04-07 | — | — | US | disclosed |
| WO-2025224249-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS AG (CH) | 2025-10-30 | — | — | WO | disclosed |
| WO-2025090727-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2025-05-01 | — | — | WO | disclosed |
| US-20240308976-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND USES THEREOF | MONTE ROSA THERAPEUTICS AG (CH) | 2024-09-19 | — | — | US | disclosed |
| EP-3558969-B1 | PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-09-18 | — | — | EP | disclosed |
| US-20240294495-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS AG (CH) | 2024-09-05 | — | — | US | disclosed |
| US-12077521-B2 | Pyrazole derivatives as MALT1 inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2024-09-03 | — | — | US | disclosed |
| US-20240158398-A1 | INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE | BLUEPRINT MEDICINES CORPORATION | 2024-05-16 | — | — | US | disclosed |
| WO-2024028169-A1 | NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2024-02-08 | — | — | WO | disclosed |
| EP-4285996-A2 | INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE | Blueprint Medicines Corporation (US) | 2023-12-06 | — | — | EP | disclosed |
| US-4580627-A | Oil recovery process and system | MARATHON OIL COMPANY (US) | 1986-04-08 | — | — | US | disclosed |
| WO-1985003696-A1 | PROCESS FOR DILUTING AQUEOUS POLYMER SOLUTIONS | MARATHON OIL COMPANY (US) | 1985-08-29 | — | — | WO | disclosed |
| EP-0148581-A1 | High solid coatings | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1985-07-17 | — | — | EP | disclosed |
| US-4517097-A | Process for diluting aqueous polymer solutions | MARATHON OIL COMPANY (US) | 1985-05-14 | — | — | US | disclosed |
| US-4503909-A | Oil recovery process and system | MARATHON OIL COMPANY (US) | 1985-03-12 | — | — | US | disclosed |
| US-4433727-A | INJECTION OF AQUEOUS POLYMER SOLUTION AND MOBILITY BUFFER | MARATHON OIL COMPANY (US) | 1984-02-28 | — | — | US | disclosed |
| US-4397748-A | PARTIALLY HYDROLYZED ADDITION POLYMER AS FLOW CONTROL AGENT | MARATHON OIL COMPANY (US) | 1983-08-09 | — | — | US | disclosed |
| US-4290485-A | PARTIALLY HYDROLYSED POLYACRYLAMIDE, CROSSLINKING | THE DOW CHEMICAL COMPANY (US) | 1981-09-22 | — | — | US | disclosed |
| US-4165431-A | Chlorination of polyolefins in the presence of complex formers | BAYER AKTIENGESELLSCHAFT (DE) | 1979-08-21 | — | — | US | disclosed |
| US-3945958-A | WATER-SOLUBLE CELLULOSE ETHERS, VISCOSITY | SHINETSU CHEMICAL COMPANY (JA) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158398-A1 | INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE | ACVR1, ACVR2A, ACVRL1 | TSHR 1171/4885 |
| US-20240294495-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | CRBN, GSPT1, GSPT2 | TSHR 2591/4885 |
| US-20240308976-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND USES THEREOF | CRBN, GSPT1, GSPT2 | TSHR 2520/4885 |
| US-12595265-B2 | Inhibitors of activin receptor-like kinase | ACVR1, ACVRL1, ACVR2A | TSHR 126/4885 |
| US-12077521-B2 | Pyrazole derivatives as MALT1 inhibitors | MALT1, PPP3R1, SQSTM1 | TSHR 4388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.