Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.41 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.37 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | CDC14B | O60729 | 1/20 | 0.35 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3888087 | 0.85 | ALOX5 (0.42) | ALOX5GGPS1C3AR1MMP12MMP13 | |
| SCHEMBL3888286 | 0.85 | ALOX5 (0.42) | ALOX5GGPS1C3AR1MMP12MMP13 | |
| SCHEMBL4472834 | 0.84 | ACE (0.45) | ALOX5GGPS1C3AR1MMP12MMP13 | |
| SCHEMBL3888219 | 0.79 | ALOX5 (0.44) | ALOX5GGPS1C3AR1MMP12MMP13 | |
| SCHEMBL3888226 | 0.79 | ALOX5 (0.44) | ALOX5GGPS1C3AR1MMP12MMP13 | |
| SCHEMBL3866502 | 0.78 | PPARA (0.42) | ALOX5GGPS1C3AR1FNTAFNTB | |
| SCHEMBL3866881 | 0.78 | PPARA (0.42) | ALOX5GGPS1C3AR1FNTAFNTB | |
| SCHEMBL5197708 | 0.77 | CYP2C19 (0.42) | ALOX5GGPS1C3AR1MMP12MMP13 | |
| SCHEMBL4459051 | 0.77 | CYP2C19 (0.51) | ALOX5GGPS1C3AR1MMP12MMP13 | |
| SCHEMBL4476792 | 0.77 | ALOX5 (0.44) | ALOX5GGPS1C3AR1MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006525365-A | — | — | 2006-11-09 | — | — | JP | claimed |
| EP-1620422-A2 | PHENYL SUBSTITUTED CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B | The Institutes for Pharmaceutical Discovery, LLC (US) | 2006-02-01 | — | — | EP | claimed |
| US-20050004369-A1 | Phenyl substituted carboxylic acids | INSTITUTES FOR PHARMACEUTICAL DISCOVERY, L.L.C. | 2005-01-06 | — | — | US | claimed |
| WO-2004099170-A2 | PHENYL SUBSTITUTED CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2004-11-18 | — | — | WO | claimed |
| US-7524878-B2 | Phenyl substituted carboxylic acids | THE INSTITUTE FOR PHARMACEUTICALS DISCOVERY LLC (US) | 2009-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004369-A1 | Phenyl substituted carboxylic acids | PTPA, PTPRS, PTPRO | ALOX5 1164/4885GGPS1 2760/4885C3AR1 3143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.