Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11579860 | 0.91 | ADORA2A (0.54) | ADORA2AKCNA3NCOA1NCOA3PTGS2 | |
| SCHEMBL10927218 | 0.89 | ADORA2A (0.60) | ADORA2AKCNA3PTGS2BRD4MAPT | |
| SCHEMBL1764840 | 0.86 | ADORA2A (0.66) | ADORA2AKCNA3PTGS2MAPTKMT2A | |
| SCHEMBL10583717 | 0.84 | ADORA2A (0.55) | ADORA2AKCNA3NCOA1NCOA3PTGS2 | |
| SCHEMBL10546429 | 0.84 | ADORA2A (0.58) | ADORA2AKCNA3PTGS2BRD4MAPT | |
| SCHEMBL11296482 | 0.83 | ADORA2A (0.51) | ADORA2AKCNA3PTGS2MAPTKMT2A | |
| SCHEMBL4482378 | 0.82 | KCNA3 (0.47) | ADORA2AKCNA3NCOA1NCOA3PTGS2 | |
| SCHEMBL4471567 | 0.81 | CES2 (0.49) | ADORA2AKCNA3MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11855727 | 0.80 | ADORA2A (0.51) | ADORA2AKCNA3MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL21816994 | 0.80 | CES2 (0.53) | ADORA2AKCNA3MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7494721-B2 | Light-emitting device, condensed polycyclic compound used therein and method for producing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2009-02-24 | — | — | US | disclosed |
| US-20060051612-A1 | Light-emitting device, condensed polycyclic compound used therein and method for producing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2006-03-09 | — | — | US | disclosed |
| EP-1589089-A1 | LIGHT-EMITTING DEVICE, CONDENSED POLYCYCLIC COMPOUND USED THEREIN AND METHOD FOR PRODUCING SAME | Nippon Kayaku Kabushiki Kaisha (JP) | 2005-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060051612-A1 | Light-emitting device, condensed polycyclic compound used therein and method for producing same | CYBA, SCO2, NQO1 | ADORA2A 2286/4885KCNA3 575/4885NCOA1 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.