⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28188435 | 0.98 | — | — | |
| SCHEMBL7413663 | 0.84 | TBXAS1 (0.40) | — | |
| SCHEMBL10529099 | 0.81 | — | — | |
| SCHEMBL31135789 | 0.77 | — | — | |
| SCHEMBL2001148 | 0.77 | — | — | |
| SCHEMBL31135787 | 0.77 | — | — | |
| SCHEMBL2884168 | 0.76 | — | — | |
| SCHEMBL29004014 | 0.76 | — | — | |
| SCHEMBL83887 | 0.76 | — | — | |
| SCHEMBL16371567 | 0.76 | TBXAS1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111229311-B | Supported imidazole ionic liquid catalyst and method for synthesizing 2-amino-3-cyano-4H-pyran compounds | 三峡大学 | 2022-03-18 | — | — | CN | claimed |
| CN-111229311-A | Supported imidazole ionic liquid catalyst and method for synthesizing 2-amino-3-cyano-4H-pyran compounds | 三峡大学 | 2020-06-05 | — | — | CN | claimed |
| EP-0149115-A2 | Derivatives of 2-(1-imidazolyl)-ethanol | BOEHRINGER INGELHEIM KG (DE) | 1985-07-24 | — | — | EP | claimed |
| US-4492795-A | Alkylcycloalkyl imidazolylmethyl ketones as fungicide intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1985-01-08 | — | — | US | claimed |
| CN-113226326-B | Organic compound | 细胞内治疗公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-114805462-B | Steroid derivative regulator and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-06-18 | — | — | CN | disclosed |
| US-11987772-B2 | Solvent composition | CENTRAL GLASS COMPANY, LIMITED (JP) | 2024-05-21 | — | — | US | disclosed |
| CN-114656514-B | Steroid derivative regulator and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-05-14 | — | — | CN | disclosed |
| US-20240043777-A1 | Composition; Cleaning Agent, Aerosol Composition, Draining Agent, Foaming Agent, or Heat-Transfer Medium Containing the Composition; System Using the Heat-Transfer Medium; And Method of Cleaning Articles | CENTRAL GLASS CO., LTD. (JP) | 2024-02-08 | — | — | US | disclosed |
| EP-3325496-B1 | METHOD OF PREPARING PHYSIOLOGICALLY ACTIVE POLYPEPTIDE CONJUGATE | HANMI PHARM IND CO LTD (KR) | 2024-02-07 | — | — | EP | disclosed |
| CN-112638928-B | Salt of steroid derivative regulator and crystal form thereof | 上海翰森生物医药科技有限公司 | 2023-12-22 | — | — | CN | disclosed |
| WO-2023159035-A1 | NEUROACTIVE STEROIDS FOR TREATMENT OF CNS-RELATED DISORDERS | SAGE THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |
| US-6339099-B1 | FOR THERAPY AND PROPHYLAXIS OF THROMBOEMBOLIC DISORDER | DUPONT PHARMACEUTICALS COMPANY | 2002-01-15 | — | — | US | disclosed |
| CN-1214685-A | Farnesyl protein transfer inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1999-04-21 | — | — | CN | disclosed |
| CN-1112117-A | Imidazole-containing inhibitors of farnesyl protein transferase | BRISTOL MYERS SQUIBB CO (US) | 1995-11-22 | — | — | CN | disclosed |
| US-4767868-A | 3-Phenyl-3-(1H-imidazol-1-ylmethyl)-2-methyl-5-[(phenylamino)methyl]isoxazolidines | PENNWALT CORPORATION (US) | 1988-08-30 | — | — | US | disclosed |
| US-4550175-A | REACTING 2,4-DICHLOROBENZYL CHLORIDE WITH 1-(2,4-DICHLOROPHENYL)-2(IMIDAZOL-1-YL)-ETHANONE OXIME | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1985-10-29 | — | — | US | disclosed |
| US-4492795-A | Alkylcycloalkyl imidazolylmethyl ketones as fungicide intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1985-01-08 | — | — | US | disclosed |
| US-4443612-A | REACTION OF A HALOKETONE WITH IMIDAZOLE AND HYDROXYLAMINE | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1984-04-17 | — | — | US | disclosed |
| US-3949076-A | GASTRIC ACID SECRETION INHIBITION | SMITHKLINE CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |