SCHEMBL4477367

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4462669	0.81	CNR2 (0.60)	CNR2PDE2ANAMPTUSP30NPC1
	SCHEMBL4472712	0.78	CNR2 (0.61)	CNR2PDE2ANAMPTUSP30NPC1
	SCHEMBL4465522	0.78	CNR2 (0.62)	CNR2PDE2ANAMPTUSP30NPC1
	SCHEMBL4489016	0.77	NPC1 (0.49)	PDE2ANAMPTUSP30NPC1RAB9A
	SCHEMBL1710753	0.77	USP30 (0.50)	PDE2ANAMPTUSP30NPC1RAB9A
	SCHEMBL4474086	0.77	CNR2 (0.82)	CNR2
	SCHEMBL12345132	0.74	MAPK14 (0.62)	CNR2MAPK14NPC1RAB9AATM
	SCHEMBL4699677	0.73	CNR2 (0.48)	CNR2PDE2ANAMPTUSP30
	SCHEMBL25453440	0.71	USP30 (0.54)	CNR2PDE2AUSP30ATMPOLB
	SCHEMBL19049384	0.71	USP30 (0.54)	CNR2PDE2AUSP30ATMPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.