Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 5/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4462669 | 0.88 | CNR2 (0.60) | CNR2SCD5PDE2ANAMPTUSP30 | |
| SCHEMBL4465522 | 0.83 | CNR2 (0.62) | CNR2SCD5PDE2ANAMPTUSP30 | |
| SCHEMBL1710753 | 0.77 | USP30 (0.50) | PDE2ANAMPTHPGDUSP30 | |
| SCHEMBL4489016 | 0.77 | NPC1 (0.49) | PDE2ANAMPTHPGDUSP30 | |
| SCHEMBL23901474 | 0.76 | SPR (0.48) | CNR2SCD5PDE2ANAMPTUSP30 | |
| SCHEMBL487499 | 0.75 | KDM4E (0.45) | CNR2PDE2AUSP30 | |
| SCHEMBL4699680 | 0.74 | CNR2 (0.47) | CNR2PDE2AUSP30 | |
| SCHEMBL23901483 | 0.74 | USP30 (0.45) | CNR2SCD5HPGDUSP30 | |
| SCHEMBL4472712 | 0.74 | CNR2 (0.61) | CNR2SCD5PDE2ANAMPTUSP30 | |
| SCHEMBL4730362 | 0.73 | USP30 (0.55) | CNR2PDE2AUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966132-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070760-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |