⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4477799 | 1.00 | — | — | |
| SCHEMBL11087989 | 0.75 | — | — | |
| SCHEMBL9534597 | 0.75 | ALDH1A1 (0.47) | — | |
| SCHEMBL11087993 | 0.75 | — | — | |
| SCHEMBL11304948 | 0.72 | ALDH1A1 (0.58) | — | |
| SCHEMBL11477546 | 0.70 | ALDH1A1 (0.56) | — | |
| SCHEMBL11219198 | 0.70 | ALDH1A1 (0.56) | — | |
| SCHEMBL10718854 | 0.70 | ALDH1A1 (0.56) | — | |
| SCHEMBL10718860 | 0.70 | ALDH1A1 (0.56) | — | |
| SCHEMBL15413419 | 0.69 | ALDH1A1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116249701-B | Substituted di (pyridin-2-yl) amine derivatives, compositions and pharmaceutical uses thereof | 上海海雁医药科技有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-116249701-A | Substituted di (pyridin-2-yl) amine derivatives, compositions and pharmaceutical uses thereof | 上海海雁医药科技有限公司 | 2023-06-09 | — | — | CN | disclosed |
| US-10174046-B2 | SHIP1 modulators and methods related thereto | AQUINOX PHARMACEUTICALS (CANADA) INC. (CA) | 2019-01-08 | — | — | US | disclosed |
| US-20180155359-A9 | SHIP1 MODULATORS AND METHODS RELATED THERETO | TARO PHARMACEUTICALS INC. (CA) | 2018-06-07 | — | — | US | disclosed |
| US-20170362250-A1 | SHIP1 MODULATORS AND METHODS RELATED THERETO | AQUINOX PHARMACEUTICALS (CANADA) INC (CA) | 2017-12-21 | — | — | US | disclosed |
| US-9765085-B2 | SHIP1 modulators and methods related thereto | AQUINOX PHARMACEUTICALS (CANADA) INC. (CA) | 2017-09-19 | — | — | US | disclosed |
| US-20170247389-A2 | SHIP1 MODULATORS AND METHODS RELATED THERETO | TARO PHARMACEUTICALS INC. (CA) | 2017-08-31 | — | — | US | disclosed |
| US-20160031899-A1 | SHIP1 MODULATORS AND METHODS RELATED THERETO | AQUINOX PHARMACEUTICALS CANADA INC (CA) | 2016-02-04 | — | — | US | disclosed |
| US-8268835-B2 | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same | PFIZER INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-7622605-B2 | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same | PFIZER INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-4119781-A | Process for preparing 4-substituted imidazole compounds | SK&F LAB CO. (US) | 1978-10-10 | — | — | US | disclosed |
| US-4104382-A | (((THIAZOLYL-, ISOTHIAZOLYL- OR PYRIDYLALKYL)THIO)ALKYL)GUANIDINE | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1978-08-01 | — | — | US | disclosed |
| US-4104472-A | Imidazolemethylphosphonium salts | SMITHKLINE CORPORATION (US) | 1978-08-01 | — | — | US | disclosed |
| US-4070475-A | THIOALKYL-, AMINOALKYL-, AND OXYALKYL- SUBSTITUTED GUANIDINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1978-01-24 | — | — | US | disclosed |
| US-4063023-A | Process for preparing 4-(hydroxymethyl)imidazole compounds | SK&F LAB CO. (US) | 1977-12-13 | — | — | US | disclosed |
| US-4049669-A | Process for preparing 5-(alkoxy- and aminoethyl thio)methylthiazole compounds | SMITHKLINE CORPORATION (US) | 1977-09-20 | — | — | US | disclosed |
| US-4024271-A | INHIBITORS OF HISTAMINE ACTIVITY | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-05-17 | — | — | US | disclosed |
| US-4022797-A | PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-05-10 | — | — | US | disclosed |
| US-4000302-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-12-28 | — | — | US | disclosed |
| US-3950333-A | HISTAMINE INHIBITORS, OXYALKYL, THIOALKYL, AMINOALKYL DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | disclosed |