Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.64 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 7/20 | 0.45 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4376136 | 0.89 | MAPK14 (0.62) | MAPK14GRM5MAOBMAOA | |
| SCHEMBL4384973 | 0.79 | MAPK14 (0.45) | MAPK14GRM5MAOBMCHR1 | |
| SCHEMBL4377189 | 0.78 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL17809533 | 0.77 | MAPK14 (0.64) | MAPK14GRM5MAOBMCHR1 | |
| SCHEMBL4381266 | 0.74 | MAPK14 (0.65) | MAPK14MAOB | |
| SCHEMBL4383280 | 0.72 | MAPK14 (0.56) | MAPK14 | |
| SCHEMBL3526500 | 0.70 | MAPK14 (0.66) | MAPK14 | |
| SCHEMBL4377202 | 0.70 | MAPK14 (0.53) | MAPK14MAOB | |
| SCHEMBL4378397 | 0.70 | NOTUM (0.53) | MAPK14 | |
| SCHEMBL4384410 | 0.70 | MAPK14 (0.48) | MAPK14MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629363-B2 | antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |