Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | ADH1B | P00325 | 1/20 | 0.43 |
| ▸ | ADH1C | P00326 | 1/20 | 0.43 |
| ▸ | ADH1A | P07327 | 1/20 | 0.43 |
| ▸ | ADH4 | P08319 | 1/20 | 0.43 |
| ▸ | ADH7 | P40394 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FDPS | P14324 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22268678 | 1.00 | OPRM1 (0.50) | OPRM1MAPTTSHRTHRBSPHK1 | |
| SCHEMBL11673597 | 1.00 | OPRM1 (0.50) | OPRM1MAPTTSHRTHRBSPHK1 | |
| SCHEMBL13127438 | 1.00 | OPRM1 (0.50) | OPRM1MAPTTSHRTHRBSPHK1 | |
| SCHEMBL24761097 | 1.00 | OPRM1 (0.50) | OPRM1MAPTTSHRTHRBSPHK1 | |
| SCHEMBL14140683 | 1.00 | OPRM1 (0.50) | OPRM1MAPTTSHRTHRBSPHK1 | |
| SCHEMBL24761602 | 1.00 | OPRM1 (0.50) | OPRM1MAPTTSHRTHRBSPHK1 | |
| SCHEMBL1896842 | 1.00 | — | — | |
| SCHEMBL10041127 | 1.00 | OPRM1 (0.50) | OPRM1MAPTTSHRTHRBSPHK1 | |
| SCHEMBL1898218 | 0.97 | — | — | |
| Dimethylamine SCHEMBL9838363 | 0.92 | MAPT (0.45) | OPRM1MAPTTSHRTHRBSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021108483-A1 | THERAPEUTIC COMPOUNDS | GENENTECH, INC. (US) | 2021-06-03 | — | — | WO | disclosed |
| US-20190015211-A1 | HYDROGEL ARTHROPLASTY DEVICE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-01-17 | — | — | US | disclosed |
| US-8981625-B2 | Organic piezoelectric material, ultrasound probe, and ultrasound image detector | KONICA MINOLTA MEDICAL & GRAPHICS, INC. (JP) | 2015-03-17 | — | — | US | disclosed |
| US-20120041314-A1 | ORGANIC PIEZOELECTRIC MATERIAL, ULTRASOUND PROBE, AND ULTRASOUND IMAGE DETECTOR | KONICA MINOLTA MEDICAL & GRAPHICS, INC. (JP) | 2012-02-16 | — | — | US | disclosed |
| US-20090234151-A1 | Preparation of Mono-/Difluorinated Hydrocarbon Compounds | RHODIA CHIMIE (FR) | 2009-09-17 | — | — | US | disclosed |
| US-20090234151-A1 | Preparation of Mono-/Difluorinated Hydrocarbon Compounds | RHODIA CHIMIE (FR) | 2009-09-17 | — | — | US | disclosed |
| US-20090234151-A1 | Preparation of Mono-/Difluorinated Hydrocarbon Compounds | RHODIA CHIMIE (FR) | 2009-09-17 | — | — | US | disclosed |
| EP-1904425-A1 | METHOD FOR PREPARING MONO- OR DIFLUORINATED HYDROCARBON COMPOUNDS | Rhodia Chimie SA (FR) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007010111-A1 | METHOD FOR PREPARING MONO- OR DIFLUORINATED HYDROCARBON COMPOUNDS | RHODIA CHIMIE (FR) | 2007-01-25 | — | — | WO | disclosed |
| US-4046819-A | Alkylation of alkyl, cycloalkyl and aralkyl halides | UOP INC. (US) | 1977-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234151-A1 | Preparation of Mono-/Difluorinated Hydrocarbon Compounds | AHR, CYP2E1, CYP2F1 | OPRM1 316/4885MAPT 3285/4885TSHR 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.