Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL4479019

CC(=O)Oc1ccc(F)cc1.N

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.61
MAPT P10636 3/20 0.55
POLB P06746 1/20 0.55
PKM P14618 1/20 0.55
ELANE P08246 2/20 0.53
HSD17B10 Q99714 1/20 0.52
GAA P10253 2/20 0.50
ALDH1A1 P00352 1/20 0.50
HSP90AA1 P07900 1/20 0.50
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
KDM4E B2RXH2 2/20 0.48
CYP3A4 P08684 2/20 0.48
TTR P02766 1/20 0.48
TP53 P04637 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CYP4F2 P78329 1/20 0.47
CYP4A11 Q02928 1/20 0.47
GLA P06280 1/20 0.47
ESR1 P03372 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL660921 0.98 LMNA (0.64) LMNAMAPTPOLBPKMELANE
Hydrochloric Acid SCHEMBL28555259 0.95 LMNA (0.61) LMNAMAPTPOLBPKMELANE
SCHEMBL27559473 0.95 LMNA (0.61) LMNAMAPTPOLBPKMELANE
SCHEMBL11578278 0.95 LMNA (0.61) LMNAMAPTPOLBPKMELANE
SCHEMBL22083773 0.91 HSD17B10 (0.63) LMNAMAPTPOLBPKMELANE
SCHEMBL269329 0.85 LMNA (0.80) LMNAMAPTPOLBPKMELANE
SCHEMBL14760365 0.83 LMNA (0.76) LMNAMAPTPOLBPKMELANE
Lithium SCHEMBL30522746 0.83 LMNA (0.76) LMNAMAPTPOLBPKMELANE
SCHEMBL14877767 0.82 KMT2A (0.50) LMNAMAPTPOLBPKMHSD17B10
SCHEMBL11100009 0.82 HSD17B10 (0.62) LMNAMAPTPOLBPKMELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1731534-B1 Aqueous dispersion of polytetrafluorethylene ASAHI GLASS CO LTD (JP) 2014-07-02 EP claimed
CN-1876709-B Aqueous dispersions of polytetrafluoroethylene and process for their production ASAHI GLASS CO LTD 2010-08-25 CN claimed
US-7514484-B2 Aqueous dispersion of polytetrafluoroethylene and process for its production ASAHI GLASS COMPANY, LIMITED (JP) 2009-04-07 US claimed
EP-1731534-A1 Aqueous dispersion of polytetrafluorethylene and process for its production Asahi Glass Company, Limited (JP) 2006-12-13 EP claimed
CN-1876709-A Aqueous dispersions of polytetrafluoroethylene and process for their production ASAHI GLASS CO LTD (JP) 2006-12-13 CN claimed
US-20060276574-A1 Aqueous dispersion of polytetrafluoroethylene and process for its production ASAHI GLASS COMPANY, LIMITED (JP) 2006-12-07 US claimed
EP-1731534-B1 Aqueous dispersion of polytetrafluorethylene ASAHI GLASS CO LTD (JP) 2014-07-02 EP disclosed
CN-1876709-B Aqueous dispersions of polytetrafluoroethylene and process for their production ASAHI GLASS CO LTD 2010-08-25 CN disclosed
US-7514484-B2 Aqueous dispersion of polytetrafluoroethylene and process for its production ASAHI GLASS COMPANY, LIMITED (JP) 2009-04-07 US disclosed
EP-1731534-A1 Aqueous dispersion of polytetrafluorethylene and process for its production Asahi Glass Company, Limited (JP) 2006-12-13 EP disclosed
CN-1876709-A Aqueous dispersions of polytetrafluoroethylene and process for their production ASAHI GLASS CO LTD (JP) 2006-12-13 CN disclosed
US-20060276574-A1 Aqueous dispersion of polytetrafluoroethylene and process for its production ASAHI GLASS COMPANY, LIMITED (JP) 2006-12-07 US disclosed