Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1049122 | 0.98 | ALDH1A1 (0.61) | ALDH1A1POLBKMT2ATLR8KCNH2 | |
| Water SCHEMBL28178859 | 0.96 | ALDH1A1 (0.59) | ALDH1A1POLBKMT2ATLR8KCNH2 | |
| SCHEMBL6115033 | 0.94 | ALDH1A1 (0.61) | ALDH1A1POLBKMT2ATLR8KCNH2 | |
| Bromide SCHEMBL29384546 | 0.93 | TLR8 (0.57) | ALDH1A1POLBKMT2ATLR8KCNH2 | |
| SCHEMBL2397143 | 0.93 | ALDH1A1 (0.59) | ALDH1A1POLBKMT2ATLR8KCNH2 | |
| SCHEMBL4364563 | 0.93 | TLR8 (0.61) | ALDH1A1POLBKMT2ATLR8KCNH2 | |
| SCHEMBL9935809 | 0.92 | ALDH1A1 (0.63) | ALDH1A1POLBKMT2ATLR8KCNH2 | |
| SCHEMBL4230811 | 0.91 | ALDH1A1 (0.58) | ALDH1A1POLBKMT2ATLR8KCNH2 | |
| SCHEMBL4225938 | 0.91 | ALDH1A1 (0.58) | ALDH1A1POLBKMT2ATLR8KCNH2 | |
| SCHEMBL4226784 | 0.91 | ALDH1A1 (0.58) | ALDH1A1POLBKMT2ATLR8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107342434-A | A kind of rechargeable aluminium battery using ordered mesopore carbon as positive electrode and preparation method thereof | 济南大学 | 2017-11-10 | — | — | CN | disclosed |
| WO-2015047647-A1 | ACTIVE IONIC LIQUID MIXTURES FOR OXIDIZING ALKYLAROMATIC COMPOUNDS | UOP LLC (US) | 2015-04-02 | — | — | WO | disclosed |
| US-20150094486-A1 | ACTIVE IONIC LIQUID MIXTURES FOR OXIDIZING ALKYLAROMATIC COMPOUNDS | UOP LLC (US) | 2015-04-02 | — | — | US | disclosed |
| WO-2009062742-A2 | POROUS SOLID ACID CATALYSTS, METHODS OF MANUFACTURING THE SAME, AND METHODS OF MANUFACTURING ORGANICS MOLECULES USING THE SAME | GRACE GMBH & CO. KG (DE) | 2009-05-22 | — | — | WO | disclosed |
| US-20060167235-A1 | Process for the preparation of ayl diazonium salts and reaction with nucleophiles | AVECIA PHARMACEUTICALS LIMTIED (GB) | 2006-07-27 | — | — | US | disclosed |
| EP-1636150-A1 | PROCESS FOR THE PREPARATION OF ARYL DIAZONIUM SALTS AND REACTION WITH NUCLEOPHILES | Avecia Pharmaceuticals Limited (GB) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004108633-A1 | PROCESS FOR THE PREPARATION OF ARYL DIAZONIUM SALTS AND REACTION WITH NUCLEOPHILES | AVECIA PHARMACEUTICALS LIMITED (GB) | 2004-12-16 | — | — | WO | disclosed |