Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.94 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TYMP | P19971 | 5/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Uric Acid SCHEMBL921153 | 1.00 | GDA (0.94) | GDAALDH1A1CYP1A2CYP2C9HPGD | |
| Uric Acid SCHEMBL30062557 | 0.97 | GDA (1.00) | GDAALDH1A1CYP1A2CYP2C9HPGD | |
| Uric Acid SCHEMBL3417988 | 0.97 | GDA (1.00) | GDAALDH1A1CYP1A2CYP2C9HPGD | |
| Uric Acid SCHEMBL7933 | 0.97 | GDA (1.00) | GDAALDH1A1CYP1A2CYP2C9HPGD | |
| Uric Acid SCHEMBL22069923 | 0.97 | GDA (1.00) | GDAALDH1A1CYP1A2CYP2C9HPGD | |
| Uric Acid SCHEMBL11473111 | 0.95 | GDA (0.84) | GDAALDH1A1CYP1A2CYP2C9HPGD | |
| Uric Acid SCHEMBL10631703 | 0.94 | GDA (0.94) | GDAALDH1A1CYP1A2CYP2C9HPGD | |
| Uric Acid SCHEMBL2434620 | 0.94 | GDA (0.94) | GDAALDH1A1CYP1A2CYP2C9HPGD | |
| Uric Acid SCHEMBL16213309 | 0.94 | GDA (0.94) | GDAALDH1A1CYP1A2CYP2C9HPGD | |
| Uric Acid SCHEMBL229866 | 0.94 | GDA (0.94) | GDAALDH1A1CYP1A2CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023068249-A1 | MEASURING REAGENT FOR CROSS-LINKED N-TELOPEPTIDE OF TYPE I COLLAGEN, PREPARATION METHOD THEREOF, AND IMMUNOASSAY METHOD USING SAME | 積水メディカル株式会社 | 2023-04-27 | — | — | WO | disclosed |
| EP-2432496-B1 | CONTROL OF URIC ACID HOMEOSTASIS | ETH ZUERICH (CH) | 2018-03-28 | — | — | EP | disclosed |
| US-20140059709-A1 | CONTROL OF URIC ACID HOMEOSTASIS | ETH ZURICH (CH) | 2014-02-27 | — | — | US | disclosed |
| EP-2432496-A1 | CONTROL OF URIC ACID HOMEOSTASIS | ETH Zurich (CH) | 2012-03-28 | — | — | EP | disclosed |
| US-20120066778-A1 | CONTROL OF URIC ACID HOMEOSTASIS | ETH ZURICH (CH) | 2012-03-15 | — | — | US | disclosed |
| WO-2010133298-A1 | CONTROL OF URIC ACID HOMEOSTASIS | ETH ZURICH (CH) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120066778-A1 | CONTROL OF URIC ACID HOMEOSTASIS | PURB, UTS2R, UPP1 | GDA 120/4885ALDH1A1 2383/4885CYP1A2 4703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.