Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.42 |
| ▸ | TSHR | P16473 | 10/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4485895 | 0.81 | CYP1A2 (0.49) | ALDH1A1TSHRHSD17B10LMNAALOX15 | |
| SCHEMBL4483240 | 0.79 | KDM4E (0.50) | ALDH1A1TSHRHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL4479319 | 0.70 | SMN1; SMN2 (0.52) | ALDH1A1LMNASMN1; SMN2NPSR1KDM4E | |
| SCHEMBL27688464 | 0.68 | CYP1A2 (0.59) | ALDH1A1LMNASMN1; SMN2NPSR1GAA | |
| SCHEMBL4494497 | 0.66 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2NPSR1KDM4E | |
| SCHEMBL4482187 | 0.66 | NR1H2 (0.52) | ALDH1A1LMNASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL4470865 | 0.66 | PTGER4 (0.64) | — | |
| SCHEMBL27669279 | 0.65 | CYP1A2 (0.49) | ALDH1A1LMNASMN1; SMN2KDM4EMEN1 | |
| Benzyl Alcohol SCHEMBL14893121 | 0.65 | TSHR (0.58) | ALDH1A1TSHRHSD17B10LMNASMN1; SMN2 | |
| Benzyl Alcohol SCHEMBL27632993 | 0.65 | TSHR (0.58) | ALDH1A1TSHRHSD17B10LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514465-B2 | Synthesis of N2-(substituted arylmethyl)-3-(substituted phenyl)indazoles as novel anti-angiogenic agents | YUNG SHIN PHARM. IND. CO., LTD. (TW) | 2009-04-07 | — | — | US | disclosed |
| EP-1659115-A1 | Synthesis of substituted 2H-indazole derivatives as anti-angiogenic agents | Yung Shin Pharm. Ind. Co., Ltd. (TW) | 2006-05-24 | — | — | EP | disclosed |