SCHEMBL448073

SCHEMBL448073

CC(C#N)SCc1ccccc1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
GAA P10253 1/20 0.44
LMNA P02545 1/20 0.44
FOLH1 Q04609 2/20 0.42
MAPT P10636 2/20 0.41
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TSHR P16473 1/20 0.40
ALOX15 P16050 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CLCN2 P51788 1/20 0.37
POLB P06746 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
CYP2C19 P33261 1/20 0.37
CYP2C9 P11712 1/20 0.37
HIF1A Q16665 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21961155 0.82 ALDH1A1 (0.50) ALDH1A1GAALMNAFOLH1MAPT
SCHEMBL7541786 0.74 ALDH1A1 (0.43) ALDH1A1GAALMNAFOLH1MAPT
SCHEMBL4215184 0.73 ALDH1A1 (0.54) ALDH1A1GAALMNAFOLH1MAPT
SCHEMBL28560174 0.73 ALDH1A1 (0.57) ALDH1A1GAALMNAFOLH1MAPT
SCHEMBL15554166 0.72 ALDH1A1 (0.47) ALDH1A1GAALMNAFOLH1MAPT
SCHEMBL448072 0.71 ALDH1A1 (0.51) ALDH1A1GAALMNAFOLH1MAPT
SCHEMBL8304503 0.70 ALDH1A1 (0.51) ALDH1A1GAALMNAFOLH1MAPT
SCHEMBL21964367 0.70 ALDH1A1 (0.51) ALDH1A1GAALMNAFOLH1MAPT
SCHEMBL11577848 0.70 FOLH1 (0.47) ALDH1A1GAAFOLH1MAPTSMN1; SMN2
SCHEMBL157592 0.70 FOLH1 (0.53) ALDH1A1LMNAFOLH1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2010537404-A 2010-12-02 JP claimed
EP-2186121-A2 COMPOSITIONS AND METHODS FOR MODIFYING A SURFACE SUITED FOR SEMICONDUCTOR FABRICATION 3M Innovative Properties Company (US) 2010-05-19 EP claimed
WO-2009023387-A2 COMPOSITIONS AND METHODS FOR MODIFYING A SURFACE SUITED FOR SEMICONDUCTOR FABRICATION 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-02-19 WO claimed
US-20080026583-A1 COMPOSITIONS AND METHODS FOR MODIFYING A SURFACE SUITED FOR SEMICONDUCTOR FABRICATION 3M INNOVATIVE PROPERTIES COMPANY 2008-01-31 US claimed
US-20250354081-A1 LUBRICATING OIL ADDITIVE COMPOSITION AND LUBRICATING OIL COMPOSITION ENEOS CORPORATION (JP) 2025-11-20 US disclosed
CN-119731294-A Lubricating oil additive composition and lubricating oil composition 引能仕株式会社 2025-03-28 CN disclosed
CN-119731296-A Lubricating oil composition 引能仕株式会社 2025-03-28 CN disclosed
CN-119731295-A Lubricating oil additive composition and lubricating oil composition 引能仕株式会社 2025-03-28 CN disclosed
EP-3878928-B1 LUBRICANT COMPOSITION ENEOS CORP (JP) 2024-05-22 EP disclosed
US-11987766-B2 Lubricating oil composition for internal combustion engine ENEOS CORPORATION (JP) 2024-05-21 US disclosed
CN-115485049-B Defoaming agent and lubricating oil composition 引能仕株式会社 2024-04-26 CN disclosed
WO-2024058124-A1 LUBRICATING OIL ADDITIVE COMPOSITION, AND LUBRICATING OIL COMPOSITION ENEOS株式会社 2024-03-21 WO disclosed
US-5744430-A BASE OIL, CALCIUM SALICYLATE DETERGENT, A ZINC DIALKYLDITHIOPHOSPHATE, A SUCCINIMIDE DISPERSANT, A PHENOL ANTIOXIDANT, MOLYBDENUM DITHIOCARBAMATE FRICTION MODIFIER, AND VISCOSITY INDEX IMPROVER NIPPON OIL CO., LTD. (JP) 1998-04-28 US disclosed
EP-0671460-B1 ELECTROVISCOUS FLUID TONEN CORP (JP) 1998-04-01 EP disclosed
US-5603861-A NONAQUEOUS; DIELECTRIC TONEN CORPORATION (JP) 1997-02-18 US disclosed
EP-0692531-A1 ELECTROVISCOUS FLUID Tonen Corporation (JP) 1996-01-17 EP disclosed
EP-0671460-A1 ELECTROVISCOUS FLUID Tonen Corporation (JP) 1995-09-13 EP disclosed
US-5387370-A Ferroelectric liquid crystals with no azomethine bonding that have spontaneous polarization of 3 x 10 to the-9th C/cm3 or more TONEN CORPORATION (JP) 1995-02-07 US disclosed
EP-0395359-B1 ELECTROVISCOUS ELECTRICALLY INSULATING FLUIDS Tonen Corporation (JP) 1993-09-22 EP disclosed
EP-0395359-A1 Electroviscous electrically insulating fluids Tonen Corporation (JP) 1990-10-31 EP disclosed