Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4480919 | 1.00 | SSTR3 (0.44) | SSTR3TAS1R3TAS1R1CTSBJAK1 | |
| SCHEMBL4480911 | 1.00 | SSTR3 (0.44) | SSTR3TAS1R3TAS1R1CTSBJAK1 | |
| SCHEMBL4485499 | 0.97 | SSTR3 (0.41) | SSTR3TAS1R3TAS1R1CTSBJAK1 | |
| SCHEMBL4485497 | 0.97 | SSTR3 (0.41) | SSTR3TAS1R3TAS1R1CTSBJAK1 | |
| SCHEMBL4485502 | 0.97 | SSTR3 (0.41) | SSTR3TAS1R3TAS1R1CTSBJAK1 | |
| SCHEMBL4487194 | 0.97 | SSTR3 (0.41) | SSTR3TAS1R3TAS1R1CTSBJAK1 | |
| SCHEMBL4499466 | 0.97 | SSTR3 (0.41) | SSTR3TAS1R3TAS1R1CTSBJAK1 | |
| SCHEMBL4501704 | 0.85 | SSTR3 (0.46) | SSTR3TAS1R3TAS1R1FKBP1AALDH1A1 | |
| SCHEMBL4501708 | 0.85 | SSTR3 (0.46) | SSTR3TAS1R3TAS1R1FKBP1AALDH1A1 | |
| SCHEMBL4487986 | 0.85 | SSTR3 (0.46) | SSTR3TAS1R3TAS1R1FKBP1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582626-B2 | 5,6-dihydro-1H-pyridin-2-one compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2009-09-01 | — | — | US | disclosed |
| US-20090111798-A1 | 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS | ANADYS PHARMACEUTICALS, INC. | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111798-A1 | 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS | HAVCR2, PYGL, HCCS | SSTR3 4729/4885TAS1R3 4286/4885TAS1R1 4108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.