⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17394565 | 0.78 | — | — | |
| SCHEMBL6959485 | 0.74 | — | — | |
| SCHEMBL21966111 | 0.73 | — | — | |
| SCHEMBL14031855 | 0.69 | CYP2C19 (0.41) | — | |
| SCHEMBL14480206 | 0.69 | — | — | |
| SCHEMBL14480207 | 0.69 | — | — | |
| SCHEMBL17074393 | 0.69 | SCN9A (0.41) | — | |
| SCHEMBL14031848 | 0.67 | CYP1A2 (0.36) | — | |
| SCHEMBL1538315 | 0.66 | ALDH1A1 (0.44) | — | |
| SCHEMBL4164173 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102911133-B | Purification method of (4R,5R)-2- dichloromethyl-4,5- dihydro-5-(4-methylsulfonyl-phenyl)-4-oxazol methanol | Shaoxing minsheng pharmaceutical co ltd | 2014-07-02 | — | — | CN | claimed |
| CN-101020666-B | Preparation of florfenicol intermediate | BAOGUI KE | 2011-09-28 | — | — | CN | claimed |
| CN-101200441-A | Preparation of thiamphenicol | BAOGUI KE (CN) | 2008-06-18 | — | — | CN | claimed |
| CN-101020666-A | Prepn of florfenicol intermediate | KE BAOGUI (CN) | 2007-08-22 | — | — | CN | claimed |
| CN-107106558-A | Having a2AAminopyrazine compounds with antagonist properties | 默沙东公司 | 2017-08-29 | — | — | CN | disclosed |
| EP-2997824-A1 | NOVEL HERBICIDES | Syngenta Participations AG. (CH) | 2016-03-23 | — | — | EP | disclosed |
| CN-105295958-A | Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element | CHI MEI CORP | 2016-02-03 | — | — | CN | disclosed |
| EP-2375898-B1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-16 | — | — | EP | disclosed |
| US-8889595-B2 | Herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-18 | — | — | US | disclosed |
| CN-102149675-B | Reagents and methods for the synthesis of beta-ketoamide as a precursor to the synthesis of immune adjuvant E6020 | EISAI R&D MAN CO LTD | 2014-08-20 | — | — | CN | disclosed |
| CN-102911133-B | Purification method of (4R,5R)-2- dichloromethyl-4,5- dihydro-5-(4-methylsulfonyl-phenyl)-4-oxazol methanol | Shaoxing minsheng pharmaceutical co ltd | 2014-07-02 | — | — | CN | disclosed |
| CN-103570705-A | Substituted N-((1', 3'-azole-4'-yl)-methyl)-4-benzoyl-hexahydropyridine compound and applications thereof | INST MEDICINAL BIOTECHNOLOGY | 2014-02-12 | — | — | CN | disclosed |
| US-4956257-A | Support with a chemically sensitized silver halide emulsion layer, a hydrophillic colloid layer with a hydrazine compound and a colorless compound with an absorption maxima outside the visible light region | FUJI PHOTO FILM CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| US-4914002-A | High contrast image, high sensitivity | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0315155-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-10 | — | — | EP | disclosed |
| EP-0314104-A2 | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-03 | — | — | EP | disclosed |
| EP-0306019-A2 | Silver halide photographic material and method for forming an image | FUJI PHOTO FILM CO., LTD. (JP) | 1989-03-08 | — | — | EP | disclosed |
| US-4769316-A | Method for restraining the formation of re-reversal negative image in direct positive silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1988-09-06 | — | — | US | disclosed |
| US-4607006-A | Silver halide photographic light-sensitive material containing non-spectral sensitizing electron donative silver halide adsorptive compound | FUJI PHOTO FILM CO., LTD. (JP) | 1986-08-19 | — | — | US | disclosed |
| US-3935010-A | IMIDAZOQUINOXALINE DESENSITIZER | EASTMAN KODAK COMPANY (US) | 1976-01-27 | — | — | US | disclosed |