Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747628 | 0.89 | — | — | |
| Boric Acid SCHEMBL29098230 | 0.85 | CA1 (0.56) | CA1CA2CA7CA9CA12 | |
| SCHEMBL4481606 | 0.85 | CA1 (0.55) | CA1CA2CA7CA9CA12 | |
| SCHEMBL28660909 | 0.75 | IDO1 (0.50) | CA1CA2CA7CA9CA12 | |
| 1,4-Dimethoxybenzene SCHEMBL21802643 | 0.74 | CA1 (1.00) | CA1CA2CA7CA9CA12 | |
| 1,4-Dimethoxybenzene SCHEMBL8489 | 0.74 | CA1 (1.00) | CA1CA2CA7CA9CA12 | |
| Anisole SCHEMBL8981550 | 0.74 | CA4 (0.78) | CA1CA2CA7CA9CA12 | |
| Anisole SCHEMBL27881445 | 0.74 | CA4 (0.78) | CA1CA2CA7CA9CA12 | |
| SCHEMBL23219878 | 0.72 | CA1 (0.58) | CA1CA2CA7CA9CA12 | |
| Anisole SCHEMBL28207978 | 0.72 | CA4 (0.74) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008126104-A2 | NOVEL PROCESS FOR PREPARATION OF ADAPALENE | INDOCO REMEDIES LIMITED (IN) | 2008-10-23 | — | — | WO | claimed |
| CN-108218717-B | Method for preparing asymmetric terphenyl compound by using bromoarylsulfonyl fluoride | 遵义医科大学 | 2020-01-07 | — | — | CN | disclosed |
| WO-2008126104-A3 | NOVEL PROCESS FOR PREPARATION OF ADAPALENE | INDOCO REMEDIES LTD (IN) | 2009-07-30 | — | — | WO | disclosed |
| WO-2008126104-A2 | NOVEL PROCESS FOR PREPARATION OF ADAPALENE | INDOCO REMEDIES LIMITED (IN) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008126104-A2 | NOVEL PROCESS FOR PREPARATION OF ADAPALENE | INDOCO REMEDIES LIMITED (IN) | 2008-10-23 | — | — | WO | disclosed |