SCHEMBL28660909

SCHEMBL28660909

COc1ccc(C[K])cc1.FB(F)F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.50
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
AGXT P21549 2/20 0.47
LTA4H P09960 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
ALDH1A1 P00352 2/20 0.45
ALOX15 P16050 2/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
TSHR P16473 1/20 0.45
ALOX12 P18054 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
SLC6A4 P31645 1/20 0.44
MAPT P10636 2/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28660910 0.87 IDO1 (0.50) IDO1CA12CA1CA2CA7
SCHEMBL25268602 0.80 IDO1 (0.50) IDO1CA12CA1CA2CA7
SCHEMBL4481609 0.75 CA1 (0.55) IDO1CA12CA1CA2CA7
SCHEMBL28656019 0.75 IDO1 (0.44) IDO1CA1CA2CA9AGXT
SCHEMBL28659468 0.72 IDO1 (0.46) IDO1AGXTTAAR1MAOB
SCHEMBL1895592 0.72 IDO1 (0.58) IDO1CA12CA1CA2CA7
SCHEMBL17099352 0.71 APLNR (0.55) IDO1CA12CA1CA2CA7
SCHEMBL25986524 0.71 LTA4H (0.81) IDO1CA12CA1CA2CA7
SCHEMBL27884 0.71 LTA4H (0.81) IDO1CA12CA1CA2CA7
SCHEMBL834551 0.71 TAAR1 (0.73) IDO1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110294776-B Method for preparing aryl phosphine oxide derivative 苏州大学 2021-12-10 CN disclosed