Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | CLK1 | P49759 | 2/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | FABP3 | P05413 | 4/20 | 0.46 |
| ▸ | FABP4 | P15090 | 4/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.44 |
| ▸ | CDC7 | O00311 | 3/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4489488 | 0.86 | FABP4 (0.51) | NPC1RAB9ACLK1CHEK1FABP3 | |
| SCHEMBL3828856 | 0.86 | FABP4 (0.56) | CHEK1FABP3FABP4FABP5KDM4E | |
| SCHEMBL13675570 | 0.78 | FABP4 (0.47) | CHEK1FABP3FABP4FABP5KDM4E | |
| SCHEMBL3825249 | 0.75 | PLA2G10 (0.43) | NPC1RAB9ACLK1CHEK1MAPT | |
| SCHEMBL13674672 | 0.75 | PLA2G10 (0.48) | NPC1RAB9ACLK1CHEK1MAPT | |
| SCHEMBL4499933 | 0.73 | CLK1 (0.56) | NPC1RAB9ACLK1CHEK1MAPT | |
| SCHEMBL1328083 | 0.70 | PLA2G10 (0.60) | NPC1RAB9ACLK1CHEK1MAPT | |
| SCHEMBL2885197 | 0.69 | NPC1 (0.58) | NPC1RAB9ACLK1CHEK1MAPT | |
| SCHEMBL16365894 | 0.68 | NPC1 (0.82) | NPC1RAB9ACLK1CHEK1KMT2A | |
| SCHEMBL10288174 | 0.68 | CDC7 (0.67) | SMN1; SMN2TRPM8CDC7DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270456-A1 | Novel chemical compounds | HASEGAWA MASAICHI | 2009-10-29 | — | — | US | disclosed |
| US-20090270456-A1 | Novel chemical compounds | HASEGAWA MASAICHI | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270456-A1 | Novel chemical compounds | HIPK3, HIPK2, HIPK1 | NPC1 3796/4885RAB9A 2187/4885CLK1 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.