⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL450992 | 0.67 | — | — | |
| SCHEMBL57064 | 0.66 | — | — | |
| SCHEMBL448312 | 0.65 | — | — | |
| SCHEMBL5908051 | 0.64 | — | — | |
| SCHEMBL7585983 | 0.64 | — | — | |
| Ammonia Solution, Strong SCHEMBL9197440 | 0.64 | PDE10A (0.42) | — | |
| Hydrochloric Acid SCHEMBL28073257 | 0.64 | PDE10A (0.42) | — | |
| Hydrochloric Acid SCHEMBL17225086 | 0.64 | PDE10A (0.42) | — | |
| Fluoride SCHEMBL27905674 | 0.64 | POLB (0.45) | — | |
| Hydrochloric Acid SCHEMBL29730080 | 0.64 | PDE10A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909082-B | Pyridine hydrazone derivatives, and preparation method and application thereof | 湖南大学 | 2022-09-13 | — | — | CN | claimed |
| CN-113121517-A | Triazole derivative and preparation method and application thereof | 中山大学 | 2021-07-16 | — | — | CN | claimed |
| CN-111909082-A | Pyridine hydrazone derivatives, and preparation method and application thereof | 湖南大学 | 2020-11-10 | — | — | CN | claimed |
| EP-2375898-B1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-16 | — | — | EP | claimed |
| EP-2675481-A1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES AND METHODS OF PREPARATION | ImmunoGen, Inc. (US) | 2013-12-25 | — | — | EP | claimed |
| EP-2675480-A1 | METHODS OF PREPARATION OF CONJUGATES | ImmunoGen, Inc. (US) | 2013-12-25 | — | — | EP | claimed |
| WO-2012112687-A1 | METHODS OF PREPARATION OF CONJUGATES | IMMUNOGEN, INC. (US) | 2012-08-23 | — | — | WO | claimed |
| WO-2012112708-A1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES AND METHODS OF PREPARATION | IMMUNOGEN, INC. (US) | 2012-08-23 | — | — | WO | claimed |
| CN-1356988-A | Phenoxy fluoropyrimidines | BAYER AG (DE) | 2002-07-03 | — | — | CN | claimed |
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | claimed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | claimed |
| CN-111909082-B | Pyridine hydrazone derivatives, and preparation method and application thereof | 湖南大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-113121517-A | Triazole derivative and preparation method and application thereof | 中山大学 | 2021-07-16 | — | — | CN | disclosed |
| CN-109942653-B | Erythromycin derivative and preparation method thereof | 北京理工大学 | 2021-06-25 | — | — | CN | disclosed |
| CN-109942654-B | Macrolide and quinolone heterocomplex and preparation method thereof | 北京理工大学 | 2021-06-11 | — | — | CN | disclosed |
| US-5541317-A | PENICILLIN DERIVATIVES, CYCLIZATION OF ESTERS OR THIOESTERS | SANKYO COMPANY, LIMITED (JP) | 1996-07-30 | — | — | US | disclosed |
| CN-1068108-A | Be used to prepare the aza cyclo-butanone derivatives of carbapenem antibiotics | SANKYO CO (JP) | 1993-01-20 | — | — | CN | disclosed |
| EP-0516486-A2 | Azetidinone derivatives useful in the preparation of carbapenem antibiotics | Sankyo Company Limited (JP) | 1992-12-02 | — | — | EP | disclosed |
| US-4139623-A | HYPOTENSIVE AGENTS | C-G CORP. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4027027-A | BETA-RECEPTOR-BLOCKERS, HYPOTENSIVES AND VALODILATORS; FOR TREATING ARRYTHMIAS AND ANGINA PECTORIS | CIBA-GEIGY CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |