Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.80 |
| ▸ | TP53 | P04637 | 1/20 | 0.80 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.67 |
| ▸ | CA1 | P00915 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 2/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA3 | P07451 | 1/20 | 0.63 |
| ▸ | TYR | P14679 | 1/20 | 0.63 |
| ▸ | DRD1 | P21728 | 1/20 | 0.63 |
| ▸ | CA4 | P22748 | 1/20 | 0.63 |
| ▸ | CA6 | P23280 | 1/20 | 0.63 |
| ▸ | CA5A | P35218 | 1/20 | 0.63 |
| ▸ | CA7 | P43166 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.63 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.63 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL27613025 | 1.00 | TSHR (0.80) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28261396 | 1.00 | TSHR (0.80) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5907979 | 0.97 | TSHR (0.75) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL20240891 | 0.97 | TSHR (0.75) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL20240888 | 0.97 | TSHR (0.75) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL9063584 | 0.97 | TSHR (0.75) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL16736991 | 0.94 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL19812471 | 0.94 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL29170961 | 0.94 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL246842 | 0.94 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025092815-A1 | SKIN MATERIAL FOR VEHICLE AND VEHICLE DECORATION COMPRISING SKIN MATERIAL | 延锋国际汽车技术有限公司 | 2025-05-08 | — | — | WO | claimed |
| CN-119331401-A | Polymer blend composition | 维吉化学有限公司 | 2025-01-21 | — | — | CN | claimed |
| WO-2024255824-A1 | RECYCLABLE SKIN FOR INTERIOR OF VEHICLE AND VEHICLE INTERIOR COMPONENT COMPRISING SAME | 延锋国际汽车技术有限公司 | 2024-12-19 | — | — | WO | claimed |
| CN-118530502-A | Skin material for carrier and carrier ornament comprising skin material | 延锋国际汽车技术有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-118528621-A | Recyclable skin for a vehicle interior and vehicle interior component comprising the same | 延锋国际汽车技术有限公司 | 2024-08-23 | — | — | CN | claimed |
| US-20240182683-A1 | STABILIZER COMPOSITION, USE OF THE STABILIZER COMPOSITION, METHOD FOR STABILIZING CONDENSATION POLYMERS AGAINST HYDROLYTIC DEGRADATION, AND HYDROLYSIS-STABILIZED COMPOSITION AND MOLDING OR MOLDED PART CONSISTING THEREOF | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2024-06-06 | — | — | US | claimed |
| US-20240182674-A1 | USE OF A STABILIZER COMPOSITION FOR STABILIZING HALOGEN-FREE RECYCLED THERMOPLASTICS, STABILIZER COMPOSITION, MASTER BATCH OR CONCENTRATE, STABILIZED PLASTIC COMPOSITION, PROCESS FOR STABILIZING HALOGEN-FREE RECYCLED THERMOPLASTICS, AND USE OF COMPOSITIONS | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2024-06-06 | — | — | US | claimed |
| EP-4308642-A1 | STABILIZER COMPOSITION, USE OF THE STABILIZER COMPOSITION, METHOD FOR STABILIZING CONDENSATION POLYMERS AGAINST HYDROLYTIC DEGRADATION, AND HYDROLYSIS-STABILIZED COMPOSITION AND MOLDING OR MOLDED PART CONSISTING THEREOF | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2024-01-24 | — | — | EP | claimed |
| CN-117186596-A | Plant polyphenol and polyepoxy copolymer modified polyester and preparation method thereof | 贵州万业包装有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-117165050-A | Plant polyphenol and maleic anhydride copolymer modified polyester and preparation method thereof | 贵州劲瑞新型包装材料有限公司 | 2023-12-05 | — | — | CN | claimed |
| US-20080177000-A1 | Composition Having Improved Adherence With an Addition-Curable Material and Composite Article Incorporating the Composition | DOW CORNING CORPORATION | 2008-07-24 | — | — | US | claimed |
| JP-2007518869-A | — | — | 2007-07-12 | — | — | JP | claimed |
| CN-1890415-A | Multicomponent fiber with polyarylene sulfide component | TICONA LLC (US) | 2007-01-03 | — | — | CN | claimed |
| EP-1706450-A1 | A COMPOSITION HAVING IMPROVED ADHERENCE WITH AN ADDITION-CURABLE MATERIAL AND COMPOSITE ARTICLE INCORPORATING THE COMPOSITION | Dow Corning Corporation (US) | 2006-10-04 | — | — | EP | claimed |
| WO-2005071006-A1 | A COMPOSITION HAVING IMPROVED ADHERENCE WITH AN ADDITION-CURABLE MATERIAL AND COMPOSITE ARTICLE INCORPORATING THE COMPOSITION | DOW CORNING CORPORATION (US) | 2005-08-04 | — | — | WO | claimed |
| EP-0547032-B2 | Polyester resin foam sheet | SEKISUI PLASTICS (JP) | 2003-08-27 | — | — | EP | claimed |
| EP-0547032-B1 | Polyester resin foam sheet | SEKISUI PLASTICS (JP) | 1998-02-25 | — | — | EP | claimed |
| EP-0390489-B1 | Polyalkylene arylate resin composition | POLYPLASTICS CO (JP) | 1996-04-03 | — | — | EP | claimed |
| CN-1109405-A | Fiber reinforced thermoplastic resin structure, process for production of same, and extruder for production of same | TORAY INDUSTRIES (JP) | 1995-10-04 | — | — | CN | claimed |
| EP-0390489-A2 | Polyalkylene arylate resin composition | POLYPLASTICS CO. LTD. (JP) | 1990-10-03 | — | — | EP | claimed |