Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA3 | P07451 | 1/20 | 0.57 |
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL29170961 | 1.00 | TSHR (0.71) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL448283 | 0.94 | TSHR (0.80) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL28261396 | 0.94 | TSHR (0.80) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL27613025 | 0.94 | TSHR (0.80) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL5907979 | 0.91 | TSHR (0.75) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL9063584 | 0.91 | TSHR (0.75) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL20240891 | 0.91 | TSHR (0.75) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL20240888 | 0.91 | TSHR (0.75) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL1403607 | 0.91 | TSHR (0.86) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL1403625 | 0.91 | TSHR (0.86) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 469 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118406282-B | Method for recycling and preparing regenerated polymer from waste mixed plastic and regenerated polymer | 化学与精细化工广东省实验室 | 2025-02-28 | — | — | CN | claimed |
| CN-119189382-A | Package and method for producing same | 宝洁公司 | 2024-12-27 | — | — | CN | claimed |
| CN-118406282-A | Method for recycling and preparing regenerated polymer from waste mixed plastic and regenerated polymer | 化学与精细化工广东省实验室 | 2024-07-30 | — | — | CN | claimed |
| CN-118003738-A | UV light conversion polyester film and preparation method thereof | 浙江建兴科技有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-114316529-B | High-transparency scratch-resistant PET (polyethylene terephthalate) composite material and preparation method thereof | 东莞市达瑞电子股份有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-113881104-B | Weather-resistant agent, weather-resistant polyester film, preparation method and application thereof | 中国石油化工股份有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-113692326-B | Electronic device case, method for manufacturing the same, and metal-resin composite | 三井化学株式会社 | 2023-08-01 | — | — | CN | claimed |
| CN-116490550-A | Molded article having metallic appearance | 宝洁公司 | 2023-07-25 | — | — | CN | claimed |
| CN-113784684-B | Multi-layer dental appliance | 3M创新有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-116323802-A | Compositions and articles of radome material of wave transmission and improved dimensions | 高新特殊工程塑料全球技术有限公司 | 2023-06-23 | — | — | CN | claimed |
| EP-2040306-A1 | SOLAR CELL BACK SURFACE SEALING SHEET | Toppan Printing Co., Ltd. (JP) | 2009-03-25 | — | — | EP | claimed |
| EP-1991602-A2 | COMPOSITION AND METHOD OF USE | Sabic Innovative Plastics IP B.V. (NL) | 2008-11-19 | — | — | EP | claimed |
| WO-2007103007-A2 | COMPOSITION AND METHOD OF USE | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2007-09-13 | — | — | WO | claimed |
| US-20070213471-A1 | COMPOSITION AND METHOD OF USE | GENERAL ELECTRIC COMPANY (US) | 2007-09-13 | — | — | US | claimed |
| EP-0683208-A2 | Transparent polycarbonate polyester blends | Bayer Corporation (US) | 1995-11-22 | — | — | EP | claimed |
| EP-0320348-B1 | Roller bottle for tissue culture growth | IN VITRO SCIENT PRODUCTS INC (US) | 1994-03-23 | — | — | EP | claimed |
| US-5010013-A | Corrugated walls, drainage channels | IN VITRO SCIENTIFIC PRODUCTS, INC. (US) | 1991-04-23 | — | — | US | claimed |
| US-4962033-A | WALL FORMED OF CORRUGATIONS, SYMMETRICAL AND PERPENDICULAR TO AXIS AND HAVING A DRAIN CHANNEL | IN VITRO SCIENTIFIC PRODUCTS (US) | 1990-10-09 | — | — | US | claimed |
| US-4610925-A | NYLON OR POLYESTER CORE, POLYMERIC SHEATH CONTAINING CARBON | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-09-09 | — | — | US | claimed |
| EP-0160320-A2 | Antistatic hairbrush filament | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-06 | — | — | EP | claimed |