SCHEMBL4482970

SCHEMBL4482970

CCCNC(=O)N(Cc1ccc(C#N)cc1)c1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1908231 0.88 MLYCD (0.67) MLYCD
SCHEMBL1898842 0.86 MLYCD (0.79) MLYCD
SCHEMBL1896871 0.85 MLYCD (0.81) MLYCD
SCHEMBL1900991 0.84 MLYCD (1.00) MLYCD
SCHEMBL4503922 0.81 MLYCD (0.66) MLYCD
SCHEMBL4496977 0.80 MLYCD (0.72) MLYCD
SCHEMBL6538355 0.79 MLYCD (1.00) MLYCD
SCHEMBL1900136 0.79 MLYCD (0.72) MLYCD
SCHEMBL1898033 0.78 MLYCD (0.69) MLYCD
SCHEMBL1901486 0.74 MLYCD (0.65) MLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7524969-B2 Malonyl-CoA decarboxylase inhibitors useful as metabolic modulators CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2009-04-28 US claimed