Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284865 | 0.81 | HCAR2 (0.56) | KMT2AHCAR2LMNAMAPK1KLK7 | |
| SCHEMBL27693738 | 0.81 | ESR1 (0.49) | KMT2AHCAR2LMNAMAPK1KLK7 | |
| SCHEMBL27261768 | 0.81 | ESR1 (0.49) | KMT2AHCAR2LMNAMAPK1KLK7 | |
| SCHEMBL10200437 | 0.81 | ESR1 (0.49) | KMT2AHCAR2LMNAMAPK1KLK7 | |
| SCHEMBL1408551 | 0.79 | ALDH1A1 (0.55) | KMT2AHCAR2LMNAMAPK1ALOX5 | |
| SCHEMBL984298 | 0.78 | CYP2D6 (0.44) | KMT2AHCAR2LMNAMAPK1HTT | |
| SCHEMBL1096587 | 0.78 | CYP2D6 (0.44) | KMT2AHCAR2LMNAMAPK1ALDH1A1 | |
| SCHEMBL27840777 | 0.78 | CYP2D6 (0.44) | KMT2AHCAR2LMNAMAPK1HTT | |
| SCHEMBL24991807 | 0.76 | KMT2A (0.43) | KMT2AHCAR2LMNAMAPK1HTT | |
| SCHEMBL28623093 | 0.76 | KMT2A (0.47) | KMT2AHCAR2LMNAMAPK1KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094292-A2 | NITRIC OXIDE-BLOCKED CROSS-LINKED TETRAMERIC HEMOGLOBIN | Ikor, Inc. (US) | 2009-09-02 | — | — | EP | claimed |
| WO-2008051689-A2 | NITRIC OXIDE-BLOCKED CROSS-LINKED TETRAMERIC HEMOGLOBIN | IKOR, INC. (US) | 2008-05-02 | — | — | WO | claimed |