Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.61 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4484599 | 1.00 | KCNH2 (0.61) | KCNH2PLAUGAAMAPTTHRB | |
| Hydrochloric Acid SCHEMBL4480673 | 0.99 | KCNH2 (0.60) | KCNH2PLAUGAAMAPTTHRB | |
| Hydrochloric Acid SCHEMBL4480676 | 0.99 | KCNH2 (0.60) | KCNH2PLAUGAAMAPTTHRB | |
| SCHEMBL4496359 | 0.86 | KCNH2 (0.75) | KCNH2PLAU | |
| SCHEMBL4496363 | 0.86 | KCNH2 (0.75) | KCNH2PLAU | |
| Hydrochloric Acid SCHEMBL4489288 | 0.85 | KCNH2 (0.74) | KCNH2PLAU | |
| Hydrochloric Acid SCHEMBL4489294 | 0.85 | KCNH2 (0.74) | KCNH2PLAU | |
| SCHEMBL13887548 | 0.81 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL4494398 | 0.79 | KCNH2 (0.50) | KCNH2PLAUGAAMAPTMEN1 | |
| SCHEMBL3577583 | 0.79 | KCNH2 (0.47) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622481-B2 | Antibacterial compounds | GLAXO GROUP LIMITED (GB) | 2009-11-24 | — | — | US | claimed |