Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 12/20 | 0.75 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4496359 | 1.00 | KCNH2 (0.75) | KCNH2PLAUKDM4EPIM1PIM3 | |
| Hydrochloric Acid SCHEMBL4489294 | 0.99 | KCNH2 (0.74) | KCNH2PLAUKDM4EPIM1PIM3 | |
| Hydrochloric Acid SCHEMBL4489288 | 0.99 | KCNH2 (0.74) | KCNH2PLAUKDM4EPIM1PIM3 | |
| SCHEMBL4485277 | 0.86 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL4485283 | 0.86 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL4485290 | 0.86 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL4484596 | 0.86 | KCNH2 (0.61) | KCNH2PLAU | |
| SCHEMBL4484599 | 0.86 | KCNH2 (0.61) | KCNH2PLAU | |
| Hydrochloric Acid SCHEMBL4485251 | 0.85 | KCNH2 (0.98) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4485249 | 0.85 | KCNH2 (0.98) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622481-B2 | Antibacterial compounds | GLAXO GROUP LIMITED (GB) | 2009-11-24 | — | — | US | claimed |