Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Phenethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.89 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.89 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.89 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.89 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.89 |
| ▸ | MAOA | P21397 | 3/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenethylamine SCHEMBL8026262 | 0.97 | HTR2A (0.94) | HTR2ATAAR1LOXL2CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL4488214 | 0.95 | TAAR1 (0.80) | HTR2ATAAR1LOXL2CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL31461079 | 0.94 | HTR2A (0.89) | HTR2ATAAR1LOXL2CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL29775159 | 0.94 | HTR2A (0.89) | HTR2ATAAR1LOXL2CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL8412421 | 0.94 | HTR2A (0.89) | HTR2ATAAR1LOXL2CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL1331271 | 0.94 | — | — | |
| Phenethylamine SCHEMBL1799333 | 0.94 | HTR2A (1.00) | HTR2ATAAR1LOXL2CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL968 | 0.94 | — | — | |
| Phenethylamine SCHEMBL1330939 | 0.94 | — | — | |
| Phenethylamine SCHEMBL1332244 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100376043-C | Active devices using threads | IBM (US) | 2008-03-19 | — | — | CN | claimed |
| CN-1610978-A | Active devices using threads | IBM (US) | 2005-04-27 | — | — | CN | claimed |
| US-6180956-B1 | Thin film transistors with organic-inorganic hybrid materials as semiconducting channels | INTERNATIONAL BUSINESS MACHINE CORP. | 2001-01-30 | — | — | US | claimed |
| WO-2024080834-A1 | METHOD FOR MANUFACTURING LEAD-FREE PEROVSKITE LIGHT ABSORBING LAYER FABRICABLE IN AMBIENT AIR, LIGHT ABSORBING LAYER MANUFACTURED THEREBY, AND PHOTODETECTOR INCLUDING SAME | 고려대학교 산학협력단 | 2024-04-18 | — | — | WO | disclosed |
| US-7491286-B2 | Patterning solution deposited thin films with self-assembled monolayers | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2009-02-17 | — | — | US | disclosed |
| CN-100376043-C | Active devices using threads | IBM (US) | 2008-03-19 | — | — | CN | disclosed |
| US-6887332-B1 | Patterning solution deposited thin films with self-assembled monolayers | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2005-05-03 | — | — | US | disclosed |
| CN-1610978-A | Active devices using threads | IBM (US) | 2005-04-27 | — | — | CN | disclosed |
| US-20040163758-A1 | Patterning solution deposited thin films with self-assembled monolayers | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2004-08-26 | — | — | US | disclosed |
| US-6180956-B1 | Thin film transistors with organic-inorganic hybrid materials as semiconducting channels | INTERNATIONAL BUSINESS MACHINE CORP. | 2001-01-30 | — | — | US | disclosed |