Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Phenethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.89 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.89 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.89 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.89 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.89 |
| ▸ | MAOA | P21397 | 3/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenethylamine SCHEMBL26668706 | 0.97 | HTR2A (0.94) | HTR2ATAAR1LOXL2CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL8026262 | 0.97 | HTR2A (0.94) | HTR2ATAAR1LOXL2CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL19815639 | 0.94 | HTR2A (0.89) | HTR2ATAAR1LOXL2CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL4485079 | 0.94 | HTR2A (0.89) | HTR2ATAAR1LOXL2CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL29775159 | 0.94 | HTR2A (0.89) | HTR2ATAAR1LOXL2CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL31461079 | 0.94 | HTR2A (0.89) | HTR2ATAAR1LOXL2CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL1331271 | 0.94 | — | — | |
| Phenethylamine SCHEMBL1799333 | 0.94 | HTR2A (1.00) | HTR2ATAAR1LOXL2CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL1332244 | 0.94 | — | — | |
| Phenethylamine SCHEMBL1330939 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120051183-A | Novel organic-inorganic hybrid perovskite semiconductor photoelectric device | 天津赛威工业技术有限公司 | 2025-05-27 | — | — | CN | claimed |
| US-12302680-B2 | Donor-acceptor interfaces for excitonic semiconductors | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2025-05-13 | — | — | US | disclosed |
| CN-118870836-A | Near-infrared-response self-driven wide-spectrum photoelectric detector and preparation method thereof | 太原理工大学 | 2024-10-29 | — | — | CN | disclosed |
| US-11964994-B2 | Two-dimensional perovskite compositions and devices therefrom | ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) | 2024-04-23 | — | — | US | disclosed |
| US-20210296602-A1 | DONOR-ACCEPTOR INTERFACES FOR EXCITONIC SEMICONDUCTORS | UNITED STATES DEPARTMENT OF ENERGY | 2021-09-23 | — | — | US | disclosed |
| US-20210175439-A1 | TWO-DIMENSIONAL PEROVSKITE COMPOSITIONS AND DEVICES THEREFROM | Alliance for Energy Innovation, LLC | 2021-06-10 | — | — | US | disclosed |
| WO-2020040844-A1 | DONOR-ACCEPTOR INTERFACES FOR EXCITONIC SEMICONDUCTORS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-02-27 | — | — | WO | disclosed |
| US-5882548-A | Luminescent organic-inorganic perovskites with a divalent rare earth metal halide framework | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1999-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11964994-B2 | Two-dimensional perovskite compositions and devices therefrom | CBX4, RHOXF2, ADORA2B | HTR2A 1148/4885TAAR1 2148/4885LOXL2 2687/4885 |
| US-20210175439-A1 | TWO-DIMENSIONAL PEROVSKITE COMPOSITIONS AND DEVICES THEREFROM | CBX4, RHOXF2, ADORA2B | HTR2A 1148/4885TAAR1 2148/4885LOXL2 2687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.