SCHEMBL4485628

SCHEMBL4485628

CCCN(c1ccc(N(CCC)C2CCCCC2)cc1)C1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.48
ADH1A P07327 2/20 0.44
ADH1C P00326 1/20 0.41
CRHR1 P34998 1/20 0.40
PGR P06401 1/20 0.38
HRH3 Q9Y5N1 2/20 0.38
HRH4 Q9H3N8 1/20 0.38
DRD3 P35462 2/20 0.36
S1PR1 P21453 1/20 0.36
S1PR3 Q99500 1/20 0.36
CHRM1 P11229 1/20 0.36
DRD2 P14416 1/20 0.36
ADRA2C P18825 1/20 0.36
SLC6A2 P23975 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
SLC6A4 P31645 1/20 0.36
ADRA1A P35348 1/20 0.36
HRH1 P35367 1/20 0.36
OPRM1 P35372 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4480536 0.93 TRPV1 (0.45) TRPV1ADH1AADH1CCRHR1PGR
SCHEMBL6881622 0.91 TRPV1 (0.46) TRPV1ADH1ACRHR1DRD3S1PR1
SCHEMBL17046111 0.89 TRPV1 (0.47) TRPV1ADH1ACRHR1HRH3DRD3
SCHEMBL4471201 0.89 TRPV1 (0.41) TRPV1ADH1AADH1CPGRHRH3
SCHEMBL17046170 0.87 DRD3 (0.46) TRPV1ADH1AADH1CCRHR1HRH3
SCHEMBL4496003 0.85 MC4R (0.44) TRPV1ADH1AADH1CPGRHRH3
SCHEMBL11461909 0.84 TRPV1 (0.52) TRPV1DRD3DRD2THRATHRB
SCHEMBL4484272 0.83 ADH1C (0.41) TRPV1ADH1AADH1CPGRHRH3
SCHEMBL4474636 0.83 ADH1C (0.41) TRPV1ADH1AADH1CPGRHRH3
SCHEMBL4482522 0.83 TRPV1 (0.38) TRPV1ADH1AADH1CPGRHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090156441-A1 Cycloalkyl phenylenediamines as deposit control agents for lubricants GREAT LAKES CHEMICAL GLOBAL, INC. 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156441-A1 Cycloalkyl phenylenediamines as deposit control agents for lubricants C5, C9, C1S TRPV1 3899/4885ADH1A 762/4885ADH1C 557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.