Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | SDHA | P31040 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CALML3 | P27482 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 3/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368120 | 0.91 | MAOA (0.51) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL13711578 | 0.91 | MAOA (0.51) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL13335202 | 0.88 | MAOA (0.51) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3368260 | 0.88 | MAOA (0.51) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3369776 | 0.87 | MAOA (0.55) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3368308 | 0.87 | MAOA (0.49) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL13711565 | 0.87 | MAOA (0.49) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3369153 | 0.86 | MAOA (0.49) | MAOAMAOBPTGS1SDHALMNA | |
| Hydrochloric Acid SCHEMBL3368616 | 0.86 | MAOA (0.55) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL14012749 | 0.86 | MAOA (0.50) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582659-B2 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof | MERCK & CO., INC. (US) | 2009-09-01 | — | — | US | disclosed |
| US-7462633-B2 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof | MERCK & CO., INC. (US) | 2008-12-09 | — | — | US | disclosed |