Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Di(Hydroxyethyl)Ether SCHEMBL28673769 | 0.96 | TSHR (0.60) | TSHRMEN1KMT2AHTTMAPT | |
| Triethylene Glycol SCHEMBL7994424 | 0.94 | MEN1 (0.63) | TSHRMEN1KMT2AHTTMAPT | |
| SCHEMBL28593055 | 0.92 | TSHR (0.52) | TSHRMEN1KMT2AHTTMAPT | |
| SCHEMBL3380392 | 0.92 | TSHR (0.52) | TSHRMEN1KMT2AHTTMAPT | |
| Di(Hydroxyethyl)Ether SCHEMBL28126799 | 0.90 | TSHR (0.62) | TSHRMEN1KMT2AHTTMAPT | |
| SCHEMBL6469526 | 0.88 | TSHR (0.56) | TSHRMEN1KMT2AHTTMAPT | |
| Di(Hydroxyethyl)Ether SCHEMBL28418344 | 0.85 | MEN1 (0.48) | TSHRMEN1KMT2AHTTMAPT | |
| SCHEMBL9511462 | 0.85 | HTT (0.56) | TSHRMEN1KMT2AHTTMAPT | |
| SCHEMBL2302583 | 0.85 | HTT (0.50) | TSHRMEN1KMT2AHTTMAPT | |
| SCHEMBL27716413 | 0.85 | HTT (0.56) | TSHRMEN1KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557156-B2 | Aqueous hydroxy-functional polyester dispersions containing urethane groups | BAYER MATERIALSCIENCE AG (DE) | 2009-07-07 | — | — | US | disclosed |
| US-20070123643-A1 | Aqueous hydroxy-functional polyester dispersions containing urethane groups | BAYER MATERIALSCIENCE AG | 2007-05-31 | — | — | US | disclosed |