Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Di(Hydroxyethyl)Ether SCHEMBL28673769 | 0.98 | TSHR (0.60) | MEN1KMT2AHTTMAPTTHRB | |
| Butoxyethanol SCHEMBL4486144 | 0.94 | TSHR (0.68) | MEN1KMT2AHTTMAPTTHRB | |
| Di(Hydroxyethyl)Ether SCHEMBL28126799 | 0.91 | TSHR (0.62) | MEN1KMT2AHTTMAPTTHRB | |
| Di(Hydroxyethyl)Ether SCHEMBL28418344 | 0.87 | MEN1 (0.48) | MEN1KMT2AHTTMAPTTHRB | |
| SCHEMBL28593055 | 0.85 | TSHR (0.52) | MEN1KMT2AHTTMAPTTHRB | |
| SCHEMBL3380392 | 0.85 | TSHR (0.52) | MEN1KMT2AHTTMAPTTHRB | |
| SCHEMBL3381794 | 0.85 | USP2 (0.45) | MEN1KMT2AHTTMAPTTHRB | |
| Triethylene Glycol SCHEMBL8373528 | 0.85 | MEN1 (0.52) | MEN1KMT2AHTTMAPTTHRB | |
| Tetraethylene Glycol SCHEMBL17421189 | 0.85 | MEN1 (0.52) | MEN1KMT2AHTTMAPTTHRB | |
| Di(Hydroxyethyl)Ether SCHEMBL7159933 | 0.84 | HTT (0.46) | MEN1KMT2AHTTMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000020517-A2 | RADIATION-CURABLE COMPOSITIONS COMPRISING MALEIMIDE COMPOUNDS AND METHOD FOR PRODUCING A SUBSTRATE WITH A CURED LAYER | DSM N.V. (NL) | 2000-04-13 | — | — | WO | disclosed |