⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11361237 | 0.77 | — | — | |
| SCHEMBL28344643 | 0.64 | — | — | |
| SCHEMBL1866401 | 0.64 | — | — | |
| SCHEMBL3542283 | 0.64 | — | — | |
| SCHEMBL2175146 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL29260638 | 0.62 | — | — | |
| SCHEMBL9935554 | 0.59 | — | — | |
| SCHEMBL8639901 | 0.59 | — | — | |
| SCHEMBL6418743 | 0.59 | — | — | |
| SCHEMBL8925977 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692112-A4 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2008-09-24 | — | — | EP | claimed |
| EP-1558589-A4 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2008-01-09 | — | — | EP | claimed |
| US-7271167-B2 | 2-(Imidazol-1-ylalkyl)-3H-quinazolin-4-one derivatives; mitotic kinesin KSP inhibitors; anticarcinogenic, antiinflammatory, and antiproliferative agents | CYTOKINETICS, INC. (US) | 2007-09-18 | — | — | US | claimed |
| EP-1692112-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2006-08-23 | — | — | EP | claimed |
| US-20060173007-A1 | Compounds, compositions, and methods | CYTOKINETICS, INC. | 2006-08-03 | — | — | US | claimed |
| EP-1670456-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | Cytokinetics, Inc. (US) | 2006-06-21 | — | — | EP | claimed |
| US-20050234037-A1 | Compounds, compositions, and methods | CYTOKINETICS, INC. | 2005-10-20 | — | — | US | claimed |
| EP-1558589-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2005-08-03 | — | — | EP | claimed |
| US-20050165089-A1 | Compounds, compositions and methods | CYTOKINETICS, INCORPORATED | 2005-07-28 | — | — | US | claimed |
| WO-2005061460-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2005-07-07 | — | — | WO | claimed |
| US-6908926-B1 | Substituted imidazoles, their preparation and use | NOVO NORDISK A/S (DK) | 2005-06-21 | — | — | US | claimed |
| WO-2005042697-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-05-12 | — | — | WO | claimed |
| WO-2004032879-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-04-22 | — | — | WO | claimed |
| CN-110799190-B | Heterocyclic compounds | 卡都瑞恩医药有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-112543764-A | Amide compound with BET proteolysis induction effect and medical application thereof | 田边三菱制药株式会社 | 2021-03-23 | — | — | CN | disclosed |
| WO-2020009176-A1 | AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF | 田辺三菱製薬株式会社 | 2020-01-09 | — | — | WO | disclosed |
| CN-1051079-C | Benzodiazepine * derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMA CO LTD (JP) | 2000-04-05 | — | — | CN | disclosed |
| US-5821241-A | INHIBIT BINDING OF FIBRINOGEN TO BLOOD PLATELETS, INHIBIT AGGREGATION OF BLOOD PLATELETS, PREVENT OR TREAT THROMBUS OR EMBOLUS FORMATION | MERCK & CO., INC. (US) | 1998-10-13 | — | — | US | disclosed |
| CN-1075717-A | Benzodiazepine * derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 1993-09-01 | — | — | CN | disclosed |
| CN-1034722-A | Triazole [4,3-a] [1,4] benzodiazepines and thieno-[3,2-f] [1,2,4] triazolo [4,3-a] [1,4] diazepine | HOFFMANN LA ROCHE (CH) | 1989-08-16 | — | — | CN | disclosed |