Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrous Acid SCHEMBL9596334 | 0.91 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1KMT2ARAB9A | |
| SCHEMBL1011103 | 0.89 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1KMT2ARAB9A | |
| SCHEMBL4915672 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1KMT2ARAB9A | |
| SCHEMBL111605 | 0.85 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1KMT2ARAB9A | |
| SCHEMBL1871761 | 0.85 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1KMT2ARAB9A | |
| SCHEMBL294341 | 0.85 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1KMT2ARAB9A | |
| SCHEMBL13286465 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1KMT2ARAB9A | |
| SCHEMBL5396492 | 0.84 | ALDH1A1 (0.72) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL1557559 | 0.84 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL27438937 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947600-A | Preparation method of 2-isopropyl valeric acid as valproic acid process impurity | 湖南省湘中制药有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-116874347-A | Preparation method of impurity dipropylvaleric acid in valproic acid process | 湖南省湘中制药有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-108569949-A | A kind of synthesis 2- hydroxyls -2-（Containing methyl fluoride）The method of propionic acid | 北京艾德旺科技发展有限公司 | 2018-09-25 | — | — | CN | claimed |
| CN-116947600-B | Preparation method of 2-isopropyl valeric acid as valproic acid process impurity | 湖南省湘中制药有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-116874347-B | Preparation method of impurity dipropylvaleric acid in valproic acid process | 湖南省湘中制药有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-11814795-B2 | Coating for recyclable paper | JL DARLING LLC (US) | 2023-11-14 | — | — | US | disclosed |
| CN-116947600-A | Preparation method of 2-isopropyl valeric acid as valproic acid process impurity | 湖南省湘中制药有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116874347-A | Preparation method of impurity dipropylvaleric acid in valproic acid process | 湖南省湘中制药有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-108569949-A | A kind of synthesis 2- hydroxyls -2-（Containing methyl fluoride）The method of propionic acid | 北京艾德旺科技发展有限公司 | 2018-09-25 | — | — | CN | disclosed |
| US-10004737-B2 | Fused imidazole and pyrazole derivatives as modulators of TNF activity | UCB BIOPHARMA SPRL (BY) | 2018-06-26 | — | — | US | disclosed |
| US-9969728-B2 | Tetrahydroimidazopyridine derivatives as modulators of TNF activity | UCB BIOPHARMA SPRL (BE) | 2018-05-15 | — | — | US | disclosed |
| US-5216012-A | Antitumor agents for intravenous administering; in organic solvent | UNIVERSITY OF TOLEDO (US) | 1993-06-01 | — | — | US | disclosed |
| US-5051415-A | Indicators used for medical diagnosis of tumors by fluorescence | THE UNIVERSITY OF TOLEDO (US) | 1991-09-24 | — | — | US | disclosed |
| US-4877872-A | DETECTING AND TREATING TUMORS | THE UNIVERSITY OF TOLEDO (US) | 1989-10-31 | — | — | US | disclosed |
| EP-0078026-B1 | ANTIBIOTIC SYNTHESIS | MERCK & CO. INC. (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0078026-A2 | Antibiotic synthesis | MERCK & CO. INC. (US) | 1983-05-04 | — | — | EP | disclosed |
| US-4225725-A | X-RAY CONTRAST MEDIA | MALLINCKRODT, INC. (US) | 1980-09-30 | — | — | US | disclosed |
| US-4160015-A | 2,4,6-Triiodobenzoic acid derivatives and their use as x-ray contrast agents | MALLINCKRODT, INC. (US) | 1979-07-03 | — | — | US | disclosed |
| US-4125599-A | 2,4,6-TRIIODO-AMIDO-BENZOIC ACIDS | MALLINCKRODT, INC. (US) | 1978-11-14 | — | — | US | disclosed |
| US-4044141-A | CORONARY DILATING, SPASMOLYTIC, HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10004737-B2 | Fused imidazole and pyrazole derivatives as modulators of TNF activity | TNF, TNFRSF1A, TNFRSF9 | ALDH1A1 1594/4885MAPK1 240/4885L3MBTL1 3102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.