Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 18/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947359 | 0.91 | ADORA2B (0.61) | ADORA2BADORA1ADORA2A | |
| SCHEMBL4350934 | 0.87 | ADORA2B (0.59) | ADORA2BADORA1ADORA2A | |
| SCHEMBL3945189 | 0.86 | ADORA2B (0.61) | ADORA2BADORA1ADORA2A | |
| SCHEMBL4029321 | 0.85 | ADORA2B (0.62) | ADORA2BADORA1ADORA2A | |
| SCHEMBL3937297 | 0.84 | ADORA2B (0.53) | ADORA2BADORA1ADORA2A | |
| SCHEMBL3940008 | 0.77 | ADORA2B (0.62) | ADORA2BADORA1ADORA2A | |
| SCHEMBL2846118 | 0.75 | ADORA2B (1.00) | ADORA2BADORA1 | |
| SCHEMBL3958757 | 0.71 | ADORA2B (0.73) | ADORA2BADORA1ADORA2A | |
| SCHEMBL2849588 | 0.71 | ADORA2B (1.00) | ADORA2BADORA1ADORA2A | |
| SCHEMBL5328585 | 0.70 | ADORA2B (0.61) | ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032797-A2 | ADENOSINE A2B RECEPTOR ANTAGONISTS | King Pharmaceuticals Research and Development Inc. (US) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008002902-A2 | ADENOSINE A2B RECEPTOR ANTAGONISTS | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2008-01-03 | — | — | WO | disclosed |