Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4504547 | 0.93 | HDAC1 (0.56) | CYP1A2HIF1AALDH1A1HDAC6HDAC1 | |
| SCHEMBL12886130 | 0.84 | HDAC6 (0.57) | ALDH1A1HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL4482513 | 0.84 | HDAC6 (0.60) | HDAC6HDAC1HDAC2HDAC8FGFR4 | |
| SCHEMBL4488599 | 0.84 | HDAC6 (0.66) | ALDH1A1HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL4489355 | 0.84 | HDAC6 (0.60) | HDAC6HDAC1HDAC2HDAC8FGFR4 | |
| SCHEMBL4483361 | 0.84 | HDAC6 (0.62) | HDAC6HDAC1HDAC2HDAC8FGFR4 | |
| SCHEMBL4494882 | 0.83 | HDAC6 (0.61) | HDAC6HDAC1HDAC2HDAC8FGFR4 | |
| SCHEMBL4491320 | 0.81 | HDAC6 (0.59) | HDAC6HDAC1HDAC2HDAC8FGFR4 | |
| SCHEMBL4484349 | 0.81 | HDAC6 (0.58) | HDAC6HDAC1HDAC2HDAC8FGFR4 | |
| SCHEMBL4487348 | 0.81 | HDAC6 (0.58) | HDAC6HDAC1HDAC2HDAC8FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632854-B2 | Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them | PFIZER ITALIA S.R.L. (IT) | 2009-12-15 | — | — | US | claimed |