⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL452450 | 0.65 | — | — | |
| SCHEMBL4805844 | 0.64 | NPC1 (0.30) | — | |
| SCHEMBL166404 | 0.63 | — | — | |
| SCHEMBL70280 | 0.57 | CYP2A6 (0.31) | — | |
| SCHEMBL449535 | 0.55 | — | — | |
| SCHEMBL2994954 | 0.47 | — | — | |
| Methane SCHEMBL1154428 | 0.46 | — | — | |
| SCHEMBL21952429 | 0.45 | CES1 (0.67) | — | |
| SCHEMBL387162 | 0.41 | — | — | |
| Hydroquinone SCHEMBL612973 | 0.38 | ALOX15 (0.89) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334408-A1 | REACTIVE MESOGENS | Merck Patent GmbH (DE) | 2024-03-13 | — | — | EP | disclosed |
| CN-117280011-A | Reactive mesogen | 默克专利股份有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-110461824-B | Method for producing polymerizable compound and solution | 日本瑞翁株式会社 | 2023-09-05 | — | — | CN | disclosed |
| CN-110382471-B | Polymerizable compound, polymerizable liquid crystal mixture, polymer, optical film, optically anisotropic body, polarizing plate, display device, antireflection film, and compound | 日本瑞翁株式会社 | 2023-09-01 | — | — | CN | disclosed |
| CN-110003008-B | Mixtures and compounds | 日本瑞翁株式会社 | 2021-11-09 | — | — | CN | disclosed |
| EP-3247701-B1 | ANTHELMINTIC COMPOUNDS, COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-09-22 | — | — | EP | disclosed |
| CN-110431454-B | Phase difference plate, multilayer phase difference plate, polarizing plate, image display device, and polymerizable compound | 日本瑞翁株式会社 | 2021-07-16 | — | — | CN | disclosed |
| CN-110088152-B | Mixture and method for producing same, polymer, optical film, optically anisotropic body, polarizing plate, display device, and antireflection film | 日本瑞翁株式会社 | 2021-02-12 | — | — | CN | disclosed |
| US-10597364-B2 | Anthelmintic compounds, compositions and method of using thereof | Boehringer Ingelheim Animal Health USA Inc. (US) | 2020-03-24 | — | — | US | disclosed |
| CN-110461824-A | Method for producing polymerizable compound and solution | ZEON CORP | 2019-11-15 | — | — | CN | disclosed |
| EP-2253615-A1 | Cyclopropyl amide derivatives | AstraZeneca AB (SE) | 2010-11-24 | — | — | EP | disclosed |
| EP-2195293-A2 | CYCLOPTOPYL AMIDE DERIVATIVES | AstraZeneca AB (SE) | 2010-06-16 | — | — | EP | disclosed |
| WO-2010062245-A1 | SPIROCYCLOBUTYL PIPERIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2010-06-03 | — | — | WO | disclosed |
| US-20100130477-A1 | Spirocyclobutyl Piperidine Derivatives | ASTRAZENECA AB (SE) | 2010-05-27 | — | — | US | disclosed |
| US-20090076020-A1 | Cyclopropyl Amide Derivatives 978 | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | US | disclosed |
| WO-2009024823-A2 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | WO | disclosed |
| US-20050085447-A1 | Pyrido[3,4-d]pyrimidine derivatives as matrix metalloproteinase-13 inhibitors | WARNER-LAMBERT COMPANY LLC | 2005-04-21 | — | — | US | disclosed |
| WO-2005016926-A1 | PYRIDO [3,4-D] PYRIMIDINE DERIVATIVES AS MATRIX METALLOPROTEINASE-13 INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-24 | — | — | WO | disclosed |
| US-6673804-B1 | PREVENTING OR TREATING ARTHRITIS (PARTICULARLY OSTEOARTHRITIS) OR INHIBITING METASTASIS, INVASION OR GROWTH OF CANCER (PARTICULARLY BREAST CANCER) | SANKYO COMPANY, LIMITED (JP) | 2004-01-06 | — | — | US | disclosed |
| EP-1069110-A1 | SULFONAMIDE DERIVATIVES | Sankyo Company Limited (JP) | 2001-01-17 | — | — | EP | disclosed |