SCHEMBL448846

SCHEMBL448846

CCC(C)C=C(C#N)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.39
LMNA P02545 2/20 0.39
ATM Q13315 1/20 0.39
SLC16A3 O15427 2/20 0.39
SLC16A1 P53985 2/20 0.39
CISD1 Q9NZ45 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.39
GPR35 Q9HC97 1/20 0.39
EGFR P00533 3/20 0.39
POLB P06746 1/20 0.37
PKM P14618 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13696929 1.00 KDM4E (0.39) KDM4ELMNAATMSLC16A3SLC16A1
SCHEMBL1275305 0.86 KDM4E (0.37) KDM4ELMNAATMSLC16A3SLC16A1
SCHEMBL1275723 0.83 POLB (0.39) KDM4ELMNAATMSLC16A3SLC16A1
SCHEMBL1274455 0.83 KDM4E (0.39) KDM4ESLC16A3SLC16A1CISD1ALDH1A1
SCHEMBL9468589 0.81 LMNA (0.36) KDM4ELMNAATMSLC16A3SLC16A1
SCHEMBL530510 0.81 ACE2 (0.41) POLB
SCHEMBL15441 0.80 KDM4E (0.42) KDM4ELMNAATMSLC16A3SLC16A1
SCHEMBL22246044 0.80 KDM4E (0.42) KDM4ELMNAATMSLC16A3SLC16A1
SCHEMBL15440 0.80 KDM4E (0.42) KDM4ELMNAATMSLC16A3SLC16A1
SCHEMBL3154527 0.80 KDM4E (0.37) KDM4ESLC16A3SLC16A1CISD1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230323137-A1 COMPOSITION FOR SEALING COATED ELECTRIC WIRE, AND COATED ELECTRIC WIRE TOAGOSEI CO. LTD. (JP) 2023-10-12 US claimed
US-9752049-B2 Optically transparent, superhydrophobic, biocompatible thin film coatings and methods for producing same UT-BATTELLE, LLC (US) 2017-09-05 US claimed
US-20150232690-A1 OPTICALLY TRANSPARENT, SUPERHYDROPHOBIC, BIOCOMPATIBLE THIN FILM COATINGS AND METHODS FOR PRODUCING SAME UT-BATTELLE, LLC (US) 2015-08-20 US claimed
US-6977278-B1 Cyanoacrylate compositions curable to flexible polymeric materials LOCTITE (R&D) LTD. (IE) 2005-12-20 US claimed
WO-2004024467-A2 SURFACE-MOUNTING SYSTEM LOCTITE (R & D) LIMITED (IE) 2004-03-25 WO claimed
EP-1360257-A1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS Loctite (R & D) Limited (IE) 2003-11-12 EP claimed
WO-2002053666-A1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS LOCTITE (R & D) LIMITED (IE) 2002-07-11 WO claimed
WO-2025119862-A1 COMPOSITION COMPRISING N-HEPTYLCYANOACRYLATE BOSTIK SA (FR) 2025-06-12 WO disclosed
EP-4567084-A1 COMPOSITION COMPRISING N-HEPTYLCYANOACRYLATE Bostik SA (FR) 2025-06-11 EP disclosed
US-12011174-B2 Occlusion systems TERUMO CORPORATION (JP) 2024-06-18 US disclosed
US-20230323137-A1 COMPOSITION FOR SEALING COATED ELECTRIC WIRE, AND COATED ELECTRIC WIRE TOAGOSEI CO. LTD. (JP) 2023-10-12 US disclosed
US-20230256133-A1 Composite Positive And Negative Poisson`s Ratio Tissue Adhesives PARK JOON BU (US) 2023-08-17 US disclosed
EP-4142622-A1 OCCLUSION SYSTEMS Terumo Corporation (JP) 2023-03-08 EP disclosed
US-20120064356-A1 Adhesive system, method of assembly of distinct components therewith TEKNOR APEX COMPANY (US) 2012-03-15 US disclosed
WO-2012033520-A1 ADHESIVE SYSTEM, METHOD OF ASSEMBLY OF DISTINCT COMPONENTS THEREWITH TEKNOR APEX COMPANY (US) 2012-03-15 WO disclosed
EP-1360257-B1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS LOCTITE R & D LTD (IE) 2007-07-25 EP disclosed
US-6977278-B1 Cyanoacrylate compositions curable to flexible polymeric materials LOCTITE (R&D) LTD. (IE) 2005-12-20 US disclosed
WO-2004024467-A2 SURFACE-MOUNTING SYSTEM LOCTITE (R & D) LIMITED (IE) 2004-03-25 WO disclosed
EP-1360257-A1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS Loctite (R & D) Limited (IE) 2003-11-12 EP disclosed
WO-2002053666-A1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS LOCTITE (R & D) LIMITED (IE) 2002-07-11 WO disclosed