Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 11/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4677378 | 0.89 | CCR3 (0.65) | CCR3DRD4SIGMAR1MEN1LMNA | |
| SCHEMBL4485562 | 0.82 | CCR3 (0.66) | CCR3DRD4SIGMAR1MEN1LMNA | |
| SCHEMBL13631396 | 0.81 | CCR3 (0.70) | CCR3DRD4SIGMAR1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL4480424 | 0.80 | CCR3 (0.69) | CCR3DRD4SIGMAR1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL4488350 | 0.80 | CCR3 (0.69) | CCR3DRD4SIGMAR1MEN1LMNA | |
| SCHEMBL4487731 | 0.80 | CCR3 (0.63) | CCR3DRD4SIGMAR1MEN1LMNA | |
| SCHEMBL5776153 | 0.79 | CCR3 (0.74) | CCR3DRD4SIGMAR1MEN1LMNA | |
| SCHEMBL5775895 | 0.78 | CCR3 (0.79) | CCR3DRD4SIGMAR1MEN1LMNA | |
| SCHEMBL4483720 | 0.78 | CCR3 (0.62) | CCR3DRD4SIGMAR1MEN1LMNA | |
| SCHEMBL30211808 | 0.78 | DRD4 (0.56) | CCR3DRD4SIGMAR1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622464-B2 | Morpholinyl-urea derivatives for use in the treatment of inflammatory diseases | GLAXO GROUP LIMITED (GB) | 2009-11-24 | — | — | US | claimed |