Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 4/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4485562 | 0.93 | CCR3 (0.66) | CCR3KCNH2MEN1KMT2ALMNA | |
| SCHEMBL13631396 | 0.92 | CCR3 (0.70) | CCR3KCNH2MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL4480424 | 0.91 | CCR3 (0.69) | CCR3KCNH2MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL4488350 | 0.91 | CCR3 (0.69) | CCR3KCNH2MEN1KMT2ALMNA | |
| SCHEMBL4487731 | 0.90 | CCR3 (0.63) | CCR3KCNH2MEN1KMT2ALMNA | |
| SCHEMBL4488910 | 0.89 | CCR3 (0.51) | CCR3KCNH2MEN1KMT2ALMNA | |
| SCHEMBL5775895 | 0.89 | CCR3 (0.79) | CCR3KCNH2MEN1KMT2ALMNA | |
| SCHEMBL6672716 | 0.88 | CCR3 (0.67) | CCR3KCNH2MEN1KMT2ALMNA | |
| SCHEMBL4483480 | 0.88 | CCR3 (0.67) | CCR3KCNH2MEN1KMT2ALMNA | |
| SCHEMBL4483720 | 0.88 | CCR3 (0.62) | CCR3KCNH2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487828-B1 | MORPHOLINYL-UREA DERIVATIVES FOR USE OF THE TREATMENT OF INFLAMATORY DISEASES | GLAXO GROUP LTD (GB) | 2008-11-05 | — | — | EP | claimed |