SCHEMBL448901

SCHEMBL448901

Cl[Si](Cl)(OCc1ccccc1)OCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
IDO1 P14902 1/20 0.48
AGXT P21549 1/20 0.46
ALDH1A1 P00352 3/20 0.45
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
SLC6A2 P23975 2/20 0.40
SLC6A3 Q01959 2/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
PTGS1 P23219 1/20 0.40
CYP2C19 P33261 1/20 0.40
PTGS2 P35354 1/20 0.40
HIF1A Q16665 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
CALM1 P0DP23 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
MAPK1 P28482 2/20 0.39
TDP1 Q9NUW8 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1318249 0.85 TSHR (0.52) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL766418 0.79 TSHR (0.57) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL22500367 0.75 TSHR (0.52) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL766784 0.75 TSHR (0.52) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL9930083 0.75 TSHR (0.52) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL2844263 0.75 TSHR (0.52) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL997761 0.75 TSHR (0.52) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL18297936 0.73 TSHR (0.50) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL10862110 0.73 TSHR (0.50) TSHRIDO1AGXTALDH1A1CA1
Ammonia Solution, Strong SCHEMBL7970091 0.73 TSHR (0.50) TSHRIDO1AGXTALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7307036-B2 Highly active alpha-olefin polymerization catalyst FORMOSA PLASTICS CORPORATION U.S.A. (US) 2007-12-11 US claimed
US-20060019821-A1 Highly active alpha-olefin polymerization catalyst FORMOSA PLASTICS CORPORATION, U.S.A. 2006-01-26 US claimed
CN-116120360-A Silyl ether connected furyl dialdehyde compound and preparation method thereof 中国科学技术大学 2023-05-16 CN disclosed
EP-2828304-B1 ETHYLENE COPOLYMERS WITH A NOVEL COMPOSITION DISTRIBUTION AND PROCESSES FOR MAKING THE SAME FORMOSA PLASTICS CORP USA (US) 2018-03-21 EP disclosed
US-9487608-B2 Ethylene copolymers with a novel composition distribution and processes for making the same FORMOSA PLASTICS CORPORATION, USA (US) 2016-11-08 US disclosed
US-9175141-B2 Cyclosiloxane-substituted polysiloxane compounds, compositions containing the compounds and methods of use thereof BIOFILM IP, LLC (US) 2015-11-03 US disclosed
EP-1238989-B1 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst MITSUI CHEMICALS INC (JP) 2015-10-07 EP disclosed
US-20150203616-A1 Ethylene Copolymers with a Novel Composition Distribution and Processes for Making the Same FORMOSA PLASTICS CORPORATION, U.S.A. 2015-07-23 US disclosed
US-8993693-B2 Ethylene copolymers with a novel composition distribution and processes for making the same FORMOSA PLASTICS CORPORATION (US) 2015-03-31 US disclosed
EP-2828304-A1 ETHYLENE COPOLYMERS WITH A NOVEL COMPOSITION DISTRIBUTION AND PROCESSES FOR MAKING THE SAME Formosa Plastics Corporation, U.S.A. (US) 2015-01-28 EP disclosed
WO-2013142793-A1 ETHYLENE COPOLYMERS WITH A NOVEL COMPOSITION DISTRIBUTION AND PROCESSES FOR MAKING THE SAME FORMOSA PLASTICS CORPORATION, USA (US) 2013-09-26 WO disclosed
US-7618913-B2 Coordination catalyst containing an organosilicon compound , nitrogen compound, transition metal compound and magnesiumon compound on catalyst support FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2009-11-17 US disclosed
US-7582712-B1 Alpha-olefins polymerization catalyst FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2009-09-01 US disclosed
WO-2008027479-A2 HIGHLY ACTIVE ALPHA-OLEFIN COPOLYMERIZATION CATALYST SYSTEM FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2008-03-06 WO disclosed
US-20080058198-A1 Highly active alpha-olefin copolymerization catalyst system FORMOSA PLASTICS CORPORATION, U.S.A. 2008-03-06 US disclosed
US-7307036-B2 Highly active alpha-olefin polymerization catalyst FORMOSA PLASTICS CORPORATION U.S.A. (US) 2007-12-11 US disclosed
US-20060019821-A1 Highly active alpha-olefin polymerization catalyst FORMOSA PLASTICS CORPORATION, U.S.A. 2006-01-26 US disclosed
US-6897176-B2 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst MITSUI CHEMICALS, INC. (JP) 2005-05-24 US disclosed
US-20020169072-A1 Olefin polymerization catalyst and process for produing Olefin polymer with the catalyst MITSUI CHEMICALS, INC. (JP) 2002-11-14 US disclosed
EP-1238989-A2 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst Mitsui Chemicals, Inc. (JP) 2002-09-11 EP disclosed