SCHEMBL2844263

SCHEMBL2844263

C[Si](C)(C)OCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
IDO1 P14902 1/20 0.48
AGXT P21549 1/20 0.46
ALDH1A1 P00352 4/20 0.45
L3MBTL1 Q9Y468 3/20 0.43
MAPK1 P28482 3/20 0.43
MAPT P10636 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
TP53 P04637 1/20 0.42
LMNA P02545 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
CYP1A2 P05177 1/20 0.40
PTGS1 P23219 1/20 0.40
SLC6A2 P23975 1/20 0.40
CYP2C19 P33261 1/20 0.40
PTGS2 P35354 1/20 0.40
SLC6A3 Q01959 1/20 0.40
HIF1A Q16665 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28603519 0.91 TSHR (0.44) TSHRIDO1AGXTALDH1A1L3MBTL1
SCHEMBL766784 0.85 TSHR (0.52) TSHRIDO1AGXTALDH1A1L3MBTL1
SCHEMBL9930083 0.85 TSHR (0.52) TSHRIDO1AGXTALDH1A1L3MBTL1
SCHEMBL4598724 0.82 ALDH1A1 (0.37) TSHRIDO1AGXTALDH1A1L3MBTL1
SCHEMBL7917734 0.81 TSHR (0.48) TSHRIDO1AGXTALDH1A1L3MBTL1
SCHEMBL18421833 0.81 TSHR (0.48) TSHRIDO1AGXTALDH1A1L3MBTL1
SCHEMBL21801207 0.81 TSHR (0.54) TSHRIDO1AGXTALDH1A1L3MBTL1
SCHEMBL23087056 0.79 TSHR (0.46) TSHRIDO1AGXTALDH1A1L3MBTL1
SCHEMBL18297913 0.79 TSHR (0.46) TSHRIDO1AGXTALDH1A1L3MBTL1
SCHEMBL18417867 0.79 TSHR (0.46) TSHRIDO1AGXTALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024007909-A1 ETCHING COMPOSITION, ETCHING METHOD AND APPLICATION 上海集成电路材料研究院有限公司 2024-01-11 WO claimed
US-11840537-B2 Preparation and application of a 5-bromoquinazoline derivative HEFEI UNIVERSITY OF TECHNOLOGY (CN) 2023-12-12 US claimed
CN-115011350-A Etching composition, etching method and application 上海集成电路材料研究院有限公司 2022-09-06 CN claimed
CN-101604607-A Coating composition for interconnection part of electrode and comprise its plasma display SAMSUNG SDI CO LTD (KR) 2009-12-16 CN claimed
EP-2014797-A2 Coating composition for interconnection part of electrode and plasma display panel including the same Samsung SDI Co., Ltd. (KR) 2009-01-14 EP claimed
US-20080303439-A1 Coating composition for interconnection part of electrode and plasma display panel including the same SAMSUNG SDI CO., LTD., A CORP. OF THE REPUBLIC OF KOREA (KR) 2008-12-11 US claimed
EP-0728362-B1 JACKET MATERIAL FOR PROTECTION OF ELECTRICAL CONDUCTORS GORE & ASS (US) 1999-08-25 EP claimed
JP-56131536-A None JP disclosed
US-20250326936-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2025-10-23 US disclosed
US-12173166-B2 Articles including surface coatings and methods to produce them MAXTERIAL, INC. (US) 2024-12-24 US disclosed
US-11912731-B2 Use of silylated formiates as hydrosilane equivalents COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2024-02-27 US disclosed
CN-117571844-A Method for detecting organic acid in human body tricarboxylic acid cycle 凯莱谱科技股份有限公司 2024-02-20 CN disclosed
WO-2024007909-A1 ETCHING COMPOSITION, ETCHING METHOD AND APPLICATION 上海集成电路材料研究院有限公司 2024-01-11 WO disclosed
EP-0416396-A2 Tetrasaccharides and process for their preparation MERCK PATENT GmbH (DE) 1991-03-13 EP disclosed
EP-0403713-A1 Novel acetylcholinesterase inhibitors MERRELL DOW PHARMACEUTICALS INC. (US) 1990-12-27 EP disclosed
US-4831091-A USING A COORDINATION CATALYST CONTAINING A SILANETRIOL OR -DIOL AS WELL AS AN AROMATIC ESTSER; ODORLESS; STEREOSPECIFIC; PARTICLE SIZES CHISSO CORPORATION (JP) 1989-05-16 US disclosed
JP-S56131536-A PREPARATION OF ACETAL MITSUI PETROCHEM IND LTD 1981-10-15 JP disclosed
US-4076758-A Synthesis of vicinal glycols MONSANTO COMPANY (US) 1978-02-28 US disclosed
US-3983265-A Method of coating a substrate with curable organopolysiloxane compositions RHONE-POULENC S.A. (FR) 1976-09-28 US disclosed
US-3933729-A Organopolysiloxane compositions which vulcanise at ambient temperature and above to yield elastomers which adhere to the most diverse supports RHONE-POULENC S.A. (FR) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912731-B2 Use of silylated formiates as hydrosilane equivalents PFAS, EPM2A, CYP2F1 TSHR 3111/4885IDO1 4355/4885AGXT 1250/4885
US-11840537-B2 Preparation and application of a 5-bromoquinazoline derivative BRI3BP, BRSK1, BRDT TSHR 1594/4885IDO1 1915/4885AGXT 1433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.